Dindial Ramotar | Hamad Bin Khalifa University
Hamad Bin Khalifa University

FACULTY BIOGRAPHIES

Dindial Ramotar

Dindial Ramotar (PhD)


Professor
College of Health and Life Sciences

  • Phone97 466 775 351
  • Office locationC-148, 1st Floor, LAS Building

Biography


Experience

Senior Scientist

Universite de Montreal, Maisonneuve-Rosemont Hospital Research Institute.

1997-2019
  • Full professor

    Universite de Montreal, Department of Medicine.

    1997 - 2019
  • Assistant Professor

    Laval University, Quebec, Canada.

    1993 - 1996
  • Post-doctoral training

    Harvard University, Boston, MA, USA.

    1989 - 1992

Education

B.Sc

McGill University, Montreal, Canada

1982
  • M.Sc

    Concordia University, Montreal, Canada

    1984
  • Ph.D

    McGill University, Montreal, Canada

    1989
  • Post-Doctoral training

    Harvard University, Cambridge, MA, USA

    1992

Selected Publications

  • Brosseau N, Ramotar D; The human organic cation transporter OCT1 and its role as a target for drug responses

    Drug Metab Rev. 2019 Sep 28:1-19. doi: 10.1080/03602532.2019.1670204. PMID: 31564168.

    2019
  • Aouida M, Ramotar D. Identification of essential yeast genes involved in polyamine resistance

    Gene. 2018 Nov 30;677:361-369. doi: 10.1016/j.gene.2018.08.066. PMID: 30153484

    2018
  • Papaluca A, Wagner JR, Saragovi HU, Ramotar D; UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans

    Sci Rep. 2018 May 1;8(1):6860. doi: 10.1038/s41598-018-25124-1. PMID: 29717169

    2018
  • Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A

    CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide; Neuro Oncol. 2018 Mar 27;20(4):484-493. doi: 10.1093/neuonc/nox178. PMID: 29036362.

    2018
  • Andreev E, Brosseau N, Carmona E, Mes-Masson AM, Ramotar D

    The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin; Sci Rep. 2016 Feb 10;6:20508. doi: 10.1038/srep20508. PMID: 26861753.

    2016
  • Wang Z, Ayoub E, Mazouzi A, Grin I, Ishchenko AA, Fan J, Yang X, Harihar T, Saparbaev M, Ramotar D; Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain

    DNA Repair (Amst). 2014 Oct;22:53-66. doi: 10.1016/j.dnarep.2014.07.010. Epub 2014 Aug 9. PMID: 25108836.

    2014
  • Yang X, Fan J, Ishchenko AA, Patel D, Saparbaev MK, Ramotar D; Functional characterization of the Caenorhabditis elegans DNA repair enzyme APN-1

    DNA Repair (Amst). 2012 Oct 1;11(10):811-22. doi: 10.1016/j.dnarep.2012.06.009. Epub 2012 Jul 20. PMID: 22819077.

    2012
  • Poschmann J, Drouin S, Jacques PE, El Fadili K, Newmarch M, Robert F, Ramotar D; The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses

    PLoS One. 2011;6(8):e23159. doi10.1371/journal.pone.0023159. PMID: 21887235.

    2011
  • Jouvet N, Poschmann J, Douville J, Marrakchi R, Ramotar D; RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation

    Biochem Biophys Res Commun. 2011 Sep 23;413(2):248-53. doi: 10.1016/j.bbrc.2011.08.079. PMID: 21884683.

    2011
  • Aouida M, Poulin R, Ramotar D; The human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5

    J Biol Chem. 2010 Feb 26;285(9):6275-84. doi: 10.1074/jbc.M109.046151. PMID: 20037140

    2010