Borbala Mifsud | Hamad Bin Khalifa University
Hamad Bin Khalifa University


Borbala Mifsud

Dr. Borbala Mifsud (PhD)

Assistant Professor
College of Health and Life Sciences

  • Phone44547244
  • Office locationB144, 1st floor, LAS building


Dr. Mifsud graduated in biology from Eotvos Lorand University in Budapest in 2006 and obtained her PhD from the Institute of Molecular Pathology in Vienna in 2010. Her work with Thomas Jenuwein involved the epigenetic characterisation of a histone methylation deficient mouse model. After her molecular biology training, she started bioinformatics in the laboratory of Professor Nicholas Luscombe at EMBL European Bioinformatics Institute (EBI) in Cambridge, and subsequently moved to UCL and the Crick Institute in London. In her postdoctoral work she focussed on developing methods for the analysis of Hi-C type data and finding new biological insights into transcriptional regulation, by applying these methods to Hi-C and capture Hi-C data sets. Dr. Mifsud joined the William Harvey Research Insitute in QMUL as an MRC eMedLab Career Development Fellow and Lecturer in 2015, where she used chromatin interaction data to understand the function of regulatory GWAS mutations. Dr. Mifsud has been an Assistant Professor at HBKU since July 2018.


Research Interests

  • Using chromatin structure information for understanding the effect of GWAS loci
  • Uncovering chromatin interactions that change during development
  • Identifying the important regulatory interactions in diseases such as leukaemia


MRC Career Development Fellow - Lecturer;

William Harvey Research Institute; Queen Mary University London, UK

2015 - 2018
  • Postdoctoral Research Fellow

    University College London and the Francis Crick Instiute, London, UK

    2012 - 2015
  • Postdoctoral Research Fellow

    EBML European Bioinformatics Institute; Cambridge, UK

    2010 - 2012
  • PhD Student

    Institute of Molecular Pathology, Vienna, Austria

    2006 - 2010
  • Diploma Student

    National Centre for Epidemiology, Budapest, Hungary

    2004 - 2006
  • Student researcher

    Department of Plant Taxonomy, Eotvos Lorand University, Budapest, Hungary

    2003 - 2004



University of Vienna, Austria

  • MSc

    Eotvos Lorand University, Hungary


Selected Publications

  • Genetic analysis of over one million people identifies 535 novel loci for blood pressure

    Nature Genetics; 2018 Sep; doi: 10.1038/s41588-018-0205-x Evangelou E.*, Warren H.R.*, Mosen-Ansorena D.*, Mifsud B.*, Pazoki R.*, He G.*, Ntritsos G.*, Dimou N.* et al

  • Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

    Nature Communications; 2018 May 16;9(1):1947. Ramírez J., Duijvenboden S.V. Ntalla I., Mifsud B., Warren H.R., Tzanis E., Orini M., Tinker A., Lambiase P.D., Munroe P.B.

  • GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data

    PLoS One; 2017 Apr 5;12(4):e0174744 Mifsud B.*, Martincorena I.*, Darbo E., Sugar R., Schoenfelder S., Fraser P., Luscombe N.M.

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Nature Genetics; 2017 Mar;49(3):403-415 Warren H.R.*, Evangelou E.*, Cabrera C.P.*, Gao H.*, Ren M*., Mifsud B.*, et al

  • Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

    Nature Genetics; 2015 Oct;47(10):1179-86 Schoenfelder S.*, Sugar R.*, Dimond A.*, Javierre B-M.*, Armstrong H.*, Mifsud B., Dimitrova E., Tavares-Cadete F., Furlan-Magaril M., Jurkowski W., Segonds-Pichon A., Wingett S., Tabbada K., Andrews S., Herman B., LeProust E., Osborne C.S., Koseki H., Fraser P., Luscombe N.M., Elderkin S.

  • Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

    Nature Genetics; 2015 Jun;47(6):598-606 Mifsud B.*, Tavares-Cadete F.*, Young A. N.*, Sugar R., Schoenfelder S., Ferreira L., Wingett S. , Andrews S., Grey W., Ewels P.A., Herman B., Happe S., Higgs A., LeProust E., Follows G.A., Fraser P., Luscombe N.M., Osborne C.S.

  • The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

    Genome Research; 2015 Apr;25(4):582-97 Schoenfelder S.*, Furlan-Magaril M.*, Mifsud B.*, Tavares-Cadete F.*, Sugar R., Javierre B-M., Nagano T., Katsman Y., Sakthidevi M., Wingett S. W., Dimitrova E., Dimond A., Edelman L. B., Elderkin S., Tabbada K., Darbo E., Andrews S., Herman B., Higgs A., LeProust E., Osborne C.S., Mitchell J.A., Luscombe N.M., Fraser P.