Dr. Ramesh Elango | Hamad Bin Khalifa University
Hamad Bin Khalifa University

FACULTY BIOGRAPHIES

Ramesh Elango

Dr. Ramesh Elango (PhD)


Postdoctoral Researcher
Translational Oncology Research Center
Qatar Biomedical Research Institute

  • Phone55 166 846
  • Office locationSegment-6,1st Floor, Building No: 2

Biography

Dr. Ramesh Elango obtained his PhD from Bharathidasan University in India. He then joined the Molecular Biology Research Lab at King Saud University, Saudi Arabia for his postdoctoral work. 

His work led to the identification of miRNA-based molecular signature associated with lymph node metastasis in breast cancer. In 2019, Dr. Elango joined Qatar Biomedical Research Institute’s Translational Oncology Research Center as a postdoctoral researcher. 

Dr. Elango has published more than 20 peer-reviewed research articles and book chapters.

 


Research Interests

  • Identification of molecular signatures associated with breast cancer resistance to chemotherapy using transcriptome and CRISPR/Cas9.
  • Identification of the microRNA and long noncoding RNAs (lncRNAs) molecular signature associated with pathological complete response to chemotherapy resistance in Triple Negative breast cancer (TNBC).
  • Functional characterization of the role of identified lncRNAs and miRNA in driving tumorogencity and treatment response.

Experience

Postdoctoral Researcher

Translational Oncology Research Center, Qatar Biomedical Research Institute, Doha, Qatar

May 2019 - Present
  • Assistant Research Professor

    Stem Cell Unit, King Saud University-Medical City Saudi Arabia

    July 2016 - April 2019
  • Biotechnology Application Specialist

    Asila-Riyadh Company, Saudi Arabia

    October 2012 - March 2016
  • Postdoctoral Researcher

    Department of Food Science and Nutrition King Saud University, Saudi Arabia

    December 2009 - September 2012

Education

Doctorate of Philosophy (Biochemistry)

Bharathidasan University, Tamil Nadu, India

2004 - 2009
  • Master of Science (Biochemistry)

    Periyar University, Tamil Nadu, India

    2001 - 2003
  • Bachelor of Science (Biochemistry)

    Periyar University, Tamil Nadu, India

    1998 - 2001

Selected Publications

  • Elango R, Vishnubalaji R, Manikandan M, Binhamdan SI, Siyal AA, Alshawakir YA, Alfayez M, Aldahmash A, Alajez NM

    Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo. Sci Rep. 2019 Sep 23;9 (1):13696. doi: 10.1038/s41598-019-50140-0.

    2019
  • Vishnubalaji R, Shaath H, Elango R, Alajez NM. Noncoding RNAs as potential mediators of resistance to cancer immunotherapy.

    Semin Cancer Biol. 2019 Nov 14. pii: S1044-579X(19)30223-8. doi: 10.1016/j.semcancer.2019.11.006.

    2019
  • Vishnubalaji R, Elango R, Al-Toub M, Manikandan M, Al-Rikabi A, Harkness L, Ditzel N, Atteya M, Hamam R, Alfayez M, Aldahmash A, Kassem M, Alajez NM.

    Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B. Sci Rep. 2019 May 30;9(1):8101. doi: 10.1038/s41598-019-44536-1.

    2019
  • Ramesh E, Alshatwi AA

    Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells. Food and Chemical Toxicology, 51: 97-105. doi: 10.1016/j.fct.2012.07.033.

    2013
  • Ramesh E, Geraldine P, Thomas PA.

    Regulatory effect of epigallocatechin gallate on expression of C-reactive protein and other inflammatory markers in an experimental model of atherosclerosis. Chemico-Biological Interactions 183: 125-32. doi: 10.1016/j.cbi.2009.09.013.

    2010