Edward Stuenkel | Hamad Bin Khalifa University
Hamad Bin Khalifa University


Dr. Edward Stuenkel

Dr. Edward Stuenkel (PhD)

Founding Dean (Retired)
College of Health and Life Sciences

  • Phone44541944
  • Office locationA571 LAS Building


Edward Stuenkel received a PhD based in Neuroscience from the University of Hawaii and conducted postdoctoral research at University of California, San Francisco and University of Michigan. Dr. Stuenkel advanced to Professor of Physiology within the Medical School at the University of Michigan. He is now Dean of the College of Health and Life Sciences at Hamad Bin Khalifa University. At the University of Michigan Dr Stuenkel also served as Director of the Neuroscience Doctoral Program. He was director of NIH supported educational training programs in neuroscience and in targeting success for students of diversity in graduate education. Dr. Stuenkel received an award for Outstanding Faculty Service in Neuroscience. He was Director of an International Graduate Education Initiative and key to leadership of a NSF supported program directed at Advancement of Neurotechnology.  NIH awards have funded Dr. Stuenkel’s research in neuroscience since 1993, with additional funding received from ADA, NSF, and AHA. He served as a regular member of a NIH study section and served as editorial board member of the Biophysical Journal. His research appears in more than 85 published articles and 6 book chapters. For his contributions to Molecular Neuroscience, he is an elected Fellow of the AAAS.      

Research Interests

Delineate molecular pathways that regulate the electrophysiological and biophysical properties of excitable membranes and relate these to dynamic modulation of neuronal excitability and neurotransmitter release. Understand the molecular components and mechanisms that operate to regulate cellular secretion of hormones and/or neurotransmitters in physiological and pathophysiological circumstances. Develop a functional map of molecular mechanisms that participate in different forms of synaptic plasticity to ultimately enable an understanding of cognition and promote effective development of therapeutics that address the myriad of mental health or neuropathological conditions where plasticity is compromised. 



College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar

2018 - present
  • Professor

    Department of Physiology, University of Michigan, Ann Arbor, MI.

    2002 - 2018
  • Director, Education/Outreach

    NSF PIRE, International Program for the Advancement of Neurotechnology

    2015 - 2018
  • Director

    Neuroscience Graduate Program, University of Michigan

    2012 - 2018
  • Director

    Global Engagement of Doctoral Education Program, Medical School

    2011 - 2018
  • Chair

    Exocytosis and Endocytosis Subgroup, Biophysical Society

  • Chair

    Biomedical Research Council, University of Michigan Medical School, Ann Arbor, MI

  • Associate Professor

    Department of Physiology, University of Michigan, Ann Arbor, MI

  • Neuroscience Graduate Program Faculty Affiliation

    University of Michigan, Ann Arbor, MI

  • Assistant Professor

    Department of Physiology, University of Michigan, Ann Arbor, MI



Ph.D., Zoology (Neuroscience)

University of Hawaii

  • M.S., Biological Sciences

    University of Nevada

  • B.S., Biological Sciences

    South Dakota State University


Selected Publications

  • The Ubiquitin-Proteasome System Functionally Links Neuronal Tomosyn-1 to Dendritic Morphology

    JBC, Feb 16;293(7):2232-2246, PubMed PMID 29269412  Saldate, J.J., Shiau, J., Cazares, V.A., and E. L. Stuenkel 2018
  • A unique homeostatic signaling pathway links synaptic inactivity to postsynaptic mTORC1

    J. Neurosci. Feb 28;38(9):2207-2225, PubMed PMID:29311141    Henry, F., Wang, X., Serrano, D., Perez, A., Carruthers, C., Stuenkel. E., and M. Sutton 2018
  • Dynamic partitioning of synaptic vesicle pools by the SNARE-binding protein tomosyn

    J. Neuroscience 2016 36(44):11208-11222; PubMed PMID: 27807164 PMCID :PMC5148239  Cazares V.A., Njus M M., Manly A., Saldate J.J., Subramani A. et al  2016
  • A combined optogenetic-knockdown strategy reveals a major role of tomosyn in mossy fiber synaptic plasticity

    Cell Reports 12, 1-9. PMCID: PMC 4423933   Ben-Simon, Y., Rodenas-Ruano, A., Alviña, K., Lam, A.D., Stuenkel, E.L., Castillo, P.E., and U. Ashery 2015
  • Distinct actions of Rab3 and Rab27 GTPases on late stages of exocytosis of insulin

    Traffic. 2014 Sep;15(9):997-1015. PMCID: PMC4140954   Cazares VA, Subramani A, Saldate JJ, Hoerauf W, Stuenkel EL 2014
  • Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation

    J Biol Chem. 2011 Apr 22;286(16):14542-53. PMCID: PMC3077652  Williams AL, Bielopolski N, Meroz D, Lam AD, Passmore DR, et al  2011
  • Mapping dynamic protein interactions to insulin secretory granule behavior with TIRF-FRET

    Biophys J. 2010 Aug 9;99(4):1311-20. PMCID: PMC2920663   Lam AD, Ismail S, Wu R, Yizhar O, Passmore DR, et al 2010
  • SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions

    Mol Biol Cell. 2008 Feb;19(2):485-97. PMCID: PMC2230580   Lam AD, Tryoen-Toth P, Tsai B, Vitale N, Stuenkel EL 2008
  • Single channels and ionic currents in peptidergic nerve terminals

    Nature. 1986 Jan 30-Feb 5;319(6052):410-2. PMID: 2418363   Lemos JR, Nordmann JJ, Cooke IM, Stuenkel EL 1986