Dr. Houari Boumediene Abdesselem

Lecturer

Core Manager

Dr. Houari Boumediene Abdesselem

Lecturer

Core Manager

Educational Qualifications

PhD in Biology

MSc in Cell and Molecular Biology

Entity

College of Health and Life Sciences

Biography

Dr. Abdesselem is a Core Manager at the Office of Vice President for Research and a Lecturer at the College of Health and Life Sciences. He obtained his PhD in Neurobiology from the University of Konstanz, Germany in 2009. His doctoral training in Prof. Stürmer’s lab focused on the function of the NOGO-66 myelin-associated proteins in nervous system regeneration. He then moved to the United States to conduct postdoctoral training at Weill Cornell Medicine (WCM)-New York and the University of Michigan-Ann Arbor, where he investigated the role of neuronal guidance molecules in developing the nervous system.

In 2012, he moved to Qatar to join WCM-Q as a Research Fellow to study the function of SIRT2 in obesity. In 2016, Dr. Abdesselem was offered the position of Laboratory Manager at QBRI to manage the Neurological Disorders Research Center where he worked in El Agnaf’s research group on alpha-synuclein proteins in Parkinson’s disease.

He made very significant contributions to the success of his research group in developing novel tools to understand the molecular pathogenesis of PD. In 2019, he successfully built the new Proteomics Core Facility and transferred new biomarker technologies to HBKU, such as Olink, Sengenics, CDI, and Quanterix. He has successfully led and managed the core facility, which became certified and fully operational in 2020. In addition to his management roles, he has published many peer-reviewed papers in high-impact factor journals.

PhD in Biology

Konstanz University, Germany

2009

MSc in Cell and Molecular Biology

Louis Pasteur University, France

2004

BSc in Cellular and Molecular Biology

Paris 11 Orsay University, France

2003

BSc in Biology

University of Oran, Algeria

2000

  • Neurodegenerative diseases
  • Proteomics
  • immunoproteomics and biomarkers discovery
  • Precision medicine

Core Manager

Office of Vice President for Research, Hamad Bin Khalifa University

2023 - Present

Guest Lecturer

College of Health and Life Sciences, Hamad Bin Khalifa University

2023 - Present

Laboratory Manager

Qatar Biomedical Research Institute, Hamad Bin Khalifa University

2016 - 2023

Postdoctoral Associate

Weill Cornell Medicine - Qatar

2012 - 2016

Postdoctoral Associate

University of Michigan, United States

2010 - 2012

El-Agnaf, O., Bensmail, I., Al-Nesf, M. A. Y., Flynn, J., Taylor, M., Majbour, N. K., Abdi, I. Y., Vaikath, N. N., Farooq, A., Vemulapalli, P. B., Schmidt, F., Ouararhni, K., Al-Siddiqi, H. H., Arredouani, A., Wijten, P., Al-Maadheed, M., Mohamed-Ali, V., Decock, J., & Abdesselem, H. B. (2023). Uncovering a neurological protein signature for severe COVID-19. Neurobiology of Disease, 182, 106147.

Mir, F. A., Abdesselem, H. B., Cyprian, F., Iskandarani, A., Doudin, A., Samra, T. A., Alkasem, M., Abdalhakam, I., Taheri, S., & Abou-Samra, A. B. (2023). Inflammatory protein signatures in individuals with obesity and metabolic syndrome. Scientific Reports, 13(1), 22185.

Schmidt, F., Abdesselem, H. B., Suhre, K., Sohail, M. U., Al-Nesf, M., Bensmail, I., Mashod, F., Sarwath, H., Bernhardt, J., Tan, T. M., Morris, P. E., Schenck, E. J., Price, D., Vaikath, N. N., Mohamed-Ali, V., Al-Maadheed, M., Arredouani, A., Decock, J., Blackburn, J. M., Choi, A. M. K., & El-Agnaf, O. M. (2023). Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system. Frontiers in Physiology, 14, 1203723.

Abdi, Y., Bartl, M., Dakna, M., Abdesselem, H., Majbour, N., Trenkwalder, C., El-Agnaf, O., & Mollenhauer, B. (2023). Cross-sectional proteomic expression in Parkinson’s disease-related proteins in drug-naïve patients vs healthy controls with longitudinal clinical follow-up. Neurobiology of Disease, 182, 105997.

Al-Nesf, M. A. Y., Abdesselem, H. B., Bensmail, I., Ibrahim, S., Saeed, W. A. H., Mohammed, S. S. I., Razok, A., Alhussain, H., Aly, R. M. A., Al Maslamani, M., Ouararhni, K., Khatib, M. Y., Ait Hussain, A., Omrani, A. S., Al-Kaabi, S., Al Khal, A., Al-Thani, A. A., Samsam, W., Farooq, A., ... Al-Ejeh, F. (2022). Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications. Nature Communications, 13(1), 946.