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Majd Hawasly

Majd Hawasly

Scientist

Office location

RC-B1-1131 / A129

Majd Hawasly

Scientist

Educational Qualifications

PhD in Informatics

MSc in Artificial Intelligence

Entity

Qatar Computing Research Institute

Division

Arabic Language Technologies

Biography

Dr. Majd Hawasly is a scientist at the Arabic Language Technologies group at Qatar Computing Research Institute. He received his PhD from the University of Edinburgh in 2014 in a topic at the intersection of robotics and machine learning. He then joined Five AI, a UK-based autonomous driving startup, where he eventually became a lead research scientist at the applied research team in motion planning and prediction. His research interest lies in developing robust and intelligent AI systems that continually learn and adapt.

PhD in Informatics

The University of Edinburgh

2014

MSc in Artificial Intelligence

Heriot-Watt University

2009

BSc in Computer Engineering

Damascus University

2006

  • Robust Intelligent Systems
  • Lifelong Learning
  • Sequential Decision Making

Scientist

Arabic Language Technologies, Qatar Computing Research Institute

2023 - Present

Lead Research Scientist

Motion Planning and Prediction, Five AI Ltd

2022 - 2023

Senior Research Scientist

Motion Planning and Prediction, Five AI Ltd

2020 - 2022

Research Scientist

Motion Planning and Prediction, Five AI Ltd

2017 - 2020

Research Fellow

School of Computing, University of Leeds

2016 - 2017

  • 2009 - 2012, The University of Edinburgh Overseas Research Scholarship Award.
Dr. Deborah Giustini

Dr. Deborah Giustini

Assistant Professor

Office location

C.01.041, First Floor, Minaretein Building

Dr. Deborah Giustini

Assistant Professor

Educational Qualifications

PhD in Sociology

MA in Translation and Interpreting Studies

Entity

College of Humanities and Social Sciences

Program

Master of Arts in Intercultural Communication

Division

Department of Language, Culture and Communication

Biography

Deborah Giustini holds a PhD in Sociology from the University of Manchester. Before joining HBKU, she was a lecturer and postdoctoral fellow at KU Leuven (where she remains a research fellow in Interpreting Studies), lecturer and teaching assistant at the School of Social Sciences and the Humanitarian and Conflict Response Institute of the University of Manchester, and a research fellow in Sociology at Higher School of Economics. She has held research visiting positions at the Warwick Business School, at Tokyo University of Foreign Studies and Sophia University (Japan).

Her research takes a sociologically-informed perspective on labour processes and digitalization in knowledge-intensive sectors, such as the language industry, and practices of intercultural communication in organizations. Deborah has recognized international expertise in practice theory, and is a member of the Practice Theory Consortium at Lancaster University.

Deborah’s expertise is also built on her experience as a language specialist accredited to the Chartered Institute of Linguists, and with international think tanks including the WBG’s Macroeconomic Policy Working Group and the Economic Change Unit. She is an active member of the European Sociological Association, the British Sociological Association, the British Universities Industrial Relations Association, and the European Group for Organizational Studies.

 

PhD in Sociology

The University of Manchester

2019

MA in Translation and Interpreting Studies

University of International Studies (UNINT)

2013

BA in Modern Languages and Intercultural Mediation

La Sapienza University of Rome

2011

  • Intercultural communication and interpreting within and beyond organizations
  • Digitalization of work and employment in knowledge-intensive sectors (e.g. the language industry)
  • Practice-based approaches to the study of knowledge change and technology
  • Sociology of interpreting and translation
  • Power and discrimination in knowledge-intensive workplaces
  • Including gender and tech-induced tensions
  • Qualitative research and ethnographic approaches

Assistant Professor

College of Humanities and Social Sciences, Hamad Bin Khalifa University

2023 - Present

Honorary Research Fellow

KU Leuven

2023 - Present

Postdoctoral Fellow and Lecturer

KU Leuven

2021 - 2023

Postdoctoral Research Fellow

National Research University Higher School of Economics

2020 - 2021

Visiting Assistant Professor

Hamad Bin Khalifa University

2021

Visiting Assistant Professor

KU Leuven

2020 - 2021

Teaching Assistant and Lecturer

The University of Manchester

2016 - 2020

  • Editorial Board Member of Sociology (Sage)
  • Editorial Board Member of Interpreting and Society (Sage)
  • International Advisory Editorial Board Member of the British Journal of Sociology (Wiley)
  • Executive Council Member of the International Association of Translation and Intercultural Studies (IATIS)
  • 2020, Leadership in Education Awards Programme (LEAP), UK Higher Education Association, Full Fellowship (FHEA)
  • 2017, Leadership in Education Awards Programme (LEAP), UK Higher Education Academy, Associate Fellowship (AFHEA)
Dr. Maria Jimenez-Andres

Dr. Maria Jimenez-Andres

Assistant Professor

Office location

C.01.031, First Floor, Minaretein Building

Dr. Maria Jimenez-Andres

Assistant Professor

Educational Qualifications

PhD in Translation and Intercultural Studies

MA in Higher Education

Entity

College of Humanities and Social Sciences

Division

Department of Language, Culture and Communication

Biography

Dr. Maria Jimenez-Andres has extensive teaching experience in the fields of translation, interpreting and languages in the UK, Spain and the UAE. As a translator and interpreter, Dr. Maria has engaged in various roles at institutions such as the Bolivarian Embassy of Venezuela and Ipsos Mori in the United Kingdom.

Dr. Maria has a degree in Translation and Interpreting, an MA in Higher Education, and a PhD in Translation and Intercultural Studies. Her dissertation was on communication and language management in organizations supporting refugees. Her commitment to this work goes beyond academia. She is active in outreach and has carried out a number of research and non-research projects with NGOs working with refugee and migrant communities in Europe and the Middle East. More recently, she has produced a documentary, Tempo, on the lives of refugee musicians.

 

PhD in Translation and Intercultural Studies

Universitat Autònoma de Barcelona, Spain

2022

MA in Higher Education

Middlesex University, London, UK

2017

BA in Translation and Interpreting (EN/FR-ES)

University of Alicante, Spain

2012

Senior Lecturer in Spanish

Translation and Interpreting; Middlesex University.

2013 - 2023

Language Consultant

Open University of Catalunya.

January 2017 - June 2017

Predoctoral researcher

The Autonomous University of Barcelona.

2019 - 2021

Translation coordinator

MedTrans at Ipsos Mori.

2015 - 2016

Translator and researcher

Embassy of the Bolivarian Republic of Venezuela in London, UK

2013 - 2014

Spanish teacher

Eton Institute

September 2012 - December 2012

  • September 2021, Utopic futures of the Mediterranean, Executive Producer Audiovisual project grant, University of the Balearic Islands.
  • 2014, Nominated Most Innovative Teacher in the Student-Led MDXSU Teaching Awards, Middlesex University, UK.
  • December 2017, Fellow of the Higher Education Academy, UK.
Dr. Kholoud K. Saleh

Dr. Kholoud K. Saleh

Research Associate

Dr. Kholoud K. Saleh

Research Associate

Educational Qualifications

PhD in Molecular, Cellular and Integrative Physiology

Bachelor’s degree in science, Biological Sciences

Entity

College of Health and Life Sciences

Biography

Dr. Saleh obtained her bachelor’s degree in Biological Sciences from Qatar University in 2014. She later joined the Ardehali Laboratory as a visiting scientist at David Geffen School of Medicine at University of California-Los Angeles (UCLA). She participated in the characterization of cardiovascular progenitor cells derived from human pluripotent stem cells. Dr. Saleh then joined Dr. Apil Pyle Laboratory as a Graduate Student Researcher; she investigated how Duchenne Muscular Dystrophy disease severity, in mouse models, impacts the systemic delivery of human skeletal muscle progenitor cells. She obtained her PhD in Molecular, Cellular and Integrative Physiology from UCLA in 2022. 

PhD in Molecular, Cellular and Integrative Physiology

University of California Los Angeles, USA

2022

Bachelor’s degree in science, Biological Sciences

Qatar University, Qatar

2014

Pre-Medical Program

Weill Cornell Medical College, Qatar

2007 - 2010

  • Human Pluripotent Stem Cells and their differentiation to Muscle Progenitor Cells
  • Muscle Physiology
  • Insulin Resistance
  • Lipid metabolism

Graduate Student Researcher

Pyle Laboratory, UCLA

April 2017 - July 2022

UCLA Teaching Assistantship Physiology and Human Biology

UCLA

Spring 2018 and Spring 2019

Visiting Scholar Researcher

Ardehali Laboratory, UCLA

Nov 2014 - Dec 2016

Undergraduate Researcher

Qatar University

2013 - 2014

Summer Undergraduate Researcher

Kotter Laboratory at Anne McLaren Laboratory for Regenerative Medicine at Cambridge University

Summer 2013

  • 2020, Biomedical, Life Sciences and Health Sciences Research Award, UCLA David Geffen School of Medicine, USA.
  • 2016 - 2022, Qatar Research Leadership Program (QRLP) - Graduate Research Scholar Fellowship, QNRF, Qatar.
  • 2014 - 2016, Qatar Research Leadership Program (QRLP) - Management Track Fellowship, QNRF, Qatar.
  • 2013 - 2014, Qatar Science Leadership Program - Undergraduate Track Fellowship, QF, Qatar.
Dr. Martin Steinhoff

Dr. Martin Steinhoff

Professor

Office location

00974 44395101

Dr. Martin Steinhoff

Professor

Educational Qualifications

PhD in Human Biology

MD Medicine Thesis

Entity

College of Health and Life Sciences

Biography

Professor Martin Steinhoff is a Professor at Hamad Bin Khalifa University. He is also the Chairman of the Department of Dermatology and Venereology, Director of the Dermatology Institute, and Director of the Translational Research Institute (TRI) at Hamad Medical Corporation (HMC). He is also a Full Professor at Weill Cornell Medical College New York, USA, Weill-Cornell Medicine-Qatar, and Qatar University. He also holds the position of residency program director for dermatology at HMC.

Professor Steinhoff studied medicine and human biology in Germany, where he received his MD, M.Sc., and PhD from the University of Marburg. After his residency in Dermatology/Venereology, he became an Assistant Professor of Dermatology at the University of Muenster in 2002, promoted from assistant to full professor in 6 years.

He holds board certificates in Dermatology, Venereology, Phlebology and Allergy. His clinical fields of interest are inflammatory skin diseases, translational medicine, and -omics technologies. Prof. Steinhoff is an established physician-scientist with a long-standing basic and clinical research background. His group has discovered several mechanisms that are now the basis for new therapies for skin diseases. He is the author of the most relevant textbooks for Dermatology on Skin Inflammation and Allergy.

For his research, Prof Steinhoff received several prestigious international research awards worldwide. He was a member of the board of directors of the European Society of Dermatology Research (ESDR) and an honorary member of several Societies for Dermatology. According to a publication in 2023, he was considered among the Top 1% of dermatologists worldwide.

PhD in Human Biology

University of Marburg, Germany

1997 - 2001

MD Medicine Thesis

University of Marburg, Germany

1986 - 1994

MSc in Human-Biology

University of Marburg, Germany

1990 - 1992

BSc in Biology

Technical University of Braunschweig, Germany

1983 - 1986

  • Neuroimmunology
  • Atopic Dermatitis
  • Psoriasis
  • Rosacea
  • Systems Medicine
  • Cell signaling
  • Identification of disease biomarkers
  • and new therapies

Director

Translational Research, Hamad Medical Corporation

2017 - Present

Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2016 - Present

Chairman

Dermatology, Venerology, Allergy, Hamad Medical Corporation

2016 - Present

Chairman and Director

Dermatology, University College Dublin, Ireland

2014 - 2016

Full Professor

Dermatology, University of California San Francisco, United States

2009 - 2013

Associate Professor

Dermatology, University of Muenster, Germany

2005 - 2011

Assistant Professor

Dermatology, University of Muenster, Germany

2003 - 2005

Scientific University Assistant

Dermatology, University of Muenster, Germany

1999 - 2003

Postdoc (MD)

Neurosciences, Cell Biology, University of California San Francisco, United States

1997 - 1999

AiP & Resident

Dermatology, Venerology, Allergy, University of Goettingen, Germany

1995 - 1997

Postgraduate clinical training (AiP)

Internal Medicine, University of Marburg, Germany

1995

Steinhoff, M., Szabo, I., Schmelz, M., & Oaklander, A. L. (2018). Neuropathic itch. The Lancet Neurology, 17(8), 709–720.

Kido-Nakahara, M., Buddenkotte, J., Kempkes, C., Ikoma, A., Cevikbas, F., Akiyama, T., Nunes, F., Seeliger, S., Hasdemir, B., Mess, C., Buhl, T., Sulk, M., Müller, F.-U., Metze, D., Bunnett, N. W., Bhargava, A., Carstens, E., Furue, M., & Steinhoff, M. (2014). Neural peptidase endothelin-converting enzyme-1 regulates endothelin-1-induced pruritus. Journal of Clinical Investigation, 124(6), 2683–2695.

Cevikbas, F., Wang, X., Akiyama, T., Kempkes, C., Savinko, T., Antal, A., Kukova, G., Buhl, T., Ikoma, A., Buddenkotte, J., Soumelis, V., Feld, M., Alenius, H., Dillon, S. R., Carstens, E., Homey, B., Basbaum, A., & Steinhoff, M. (2014). A sensory neuron-expressed interleukin-31 receptor mediates T-helper cell-dependent itch: Involvement of TRPV1 and TRPA1. Journal of Allergy and Clinical Immunology, 133(2), 448–460.e7.

Affara, N. I., Ruffell, B., Medler, T. R., Gunderson, A. J., Johansson, M., Bornstein, S., Bergsland, E., Steinhoff, M., Li, Y., Gong, Q., Ma, Y., Wiesen, J. F., Wong, M. H., Kulesz-Martin, M., Irving, B., & Coussens, L. M. (2014). B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas. Cancer Cell, 25(6), 809–821.

Steinhoff, M., Vergnolle, N., Young, S. H., Tognetto, M., Amadesi, S., Ennes, H. S., Trevisani, M., Hollenberg, M. D., Wallace, J. L., Caughey, G. H., Mitchell, S. E., Williams, L. M., Geppetti, P., Mayer, E. A., & Bunnett, N. W. (2000). Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nature Medicine, 6(2), 151–158.

  • 2024; Qatar Foundation QNRF Award Precision Medicine Research, 3 years.
  • 2016; SFI-Pfizer Innovation Research Award from Minister of Health, Ireland (Development of biologic) Science Foundation Ireland
  • 2011; NIH R01 Research Award, NIAMS (5 years. 3 Mio US $ with overhead), P.I. 8th percentile.
  • 2001; Oskar-Gans Main research award, German Society of Dermatology, Berlin, Germany, May 5, 2001 (Protease-activated receptors and neuroinflammation and pruritus).
  • 1997; NIH-Scholarship (University of California, San Francisco, CA, USA (Depts. of Physiology & Surgery, Prof. Dr. N. Bunnett), 3 years, NIH grant.
Umm-Kulthum Ismail Umlai

Dr. Umm-Kulthum Ismail Umlai

Post-doctoral Researcher

Dr. Umm-Kulthum Ismail Umlai

Post-doctoral Researcher

Educational Qualifications

PhD in Genomics and Precision Medicine

Master in Biomedical Research

Entity

College of Health and Life Sciences

Biography

Umm-Kulthum is an early career researcher with experience in genomics, metagenomics, biomedical research and metabolomics. She spent most of her life in Qatar where she also graduated with research honours from Carnegie Mellon University located at the prestigious Education City. Her postgraduate experience involved several biomedical research projects including metabolomics of Alzheimer’s disease and liver diseases at Imperial College of Science, Technology and Medicine in the UK. Her PhD research with Hamad Bin Khalifa University was a combination of clinical and genomics research, looking into the genetics underlying rare growth disorders in paediatric patients recruited from a hospital in Qatar. Currently, Umm-Kulthum is working as a post-doctoral researcher with Professor Omar Albagha where she is involved in numerous Genome-Wide Association Studies projects which utilize the Qatar Genome Programme data to investigate various traits.

PhD in Genomics and Precision Medicine

Hamad Bin Khalifa University (Doha, Qatar)

2022

Master in Biomedical Research

Imperial College of Science Technology and Medicine (London, England)

2017

Bachelor in Biological Sciences

Carnegie Mellon University (Doha, Qatar)

2016

Post-Doctoral Researcher

Hamad Bin Khalifa University (Doha, Qatar)

2022 - Present

Teaching Assistant Pharmacogenomics Course

Hamad Bin Khalifa University (Doha, Qatar)

2021 - 2021

Research Assistant

Queen Mary University of London, (London, England)

2016 - 2017

Research Student

Biological Sciences Department, Carnegie Mellon University (Doha, Qatar)

2014 - 2016

Summer Research Fellow

Mellon College of Science, Carnegie Mellon University (Pittsburgh, USA)

2013

  • Hamad Bin Khalifa University sponsored PhD scholarship from Hamad Bin Khalifa University (Doha, Qatar), 2018 - 2022.
  • Research Honors from Research Honors, 2016.
  • Meeting of the Minds- 3rd place annual research showcase from Carnegie Mellon University (Doha, Qatar), 2015.
  • Annual Research Award- 1st place student poster (Energy and Environment category) from Annual Research Conference Qatar Foundation, 2014.
Luigia Ingianni

Luigia Ingianni

Adjunct Professor

Luigia Ingianni

Adjunct Professor

Educational Qualifications

Program on Negotiation

Women in Leadership Program

Entity

College of Law

Biography

Luigia is an employment lawyer and policy maker with more than 25 years of exponential experience in labor laws, conciliation and adjudication of employment disputes, leadership and organizational behavior, across different countries and legal systems (common and civil law jurisdictions).

She holds a Master Degree in Law, a Post-Degree Master in Human Resources and Communication, a Women in Leadership Executive Program with London Business School and is a qualified conciliator and mediator of labor disputes certified by the International Training Centre of the International Labour Organisation (ITCILO) and trained by Harvard Law School – Program on Negotiation (PON).

She has established the first administrative employment dispute resolution center in the Middle East operating under the ILO guidelines and is also a certified ITCILO Participatory Gender Audit (PGA) Facilitator, specialized in gender and organizational change.

Policy maker and advocate for justice, Luigia has designed innovative legislation and policies with particular focus on gender equality, decent work, harassment and violence in the workplace, justice and partnerships - UN SDGs 5, 8, 16 and 17 and is also a member of the WHO working group of the World of Work Dialogue.

 

Program on Negotiation

Harvard Law School

2020

Women in Leadership Program

London Business School

2019

Professional Certificate Data Protection Officer

European Centre for Privacy and Cybersecurity (ECPC), Maastricht University – The Netherlands

2018

Post Degree Master in Human Resources Communication

Superior Institute of Communication, Milan, Italy

2000

Bachelor and Master Degree in Law

University of Palermo – Italy

1995

Labor Law Consultant

Ispettorato Regionale del Lavoro – Palermo, Italy

1992

  • World-of-work-related topics

Adjunct Professor

HBKU College of Law

2022 - Present

Commissioner of the Employment Standards Office

Qatar Financial Centre

2015 - Present

Manager of International Department

Qatar International Law Firm

2012 - 2015

Owner

Studio Ingianni Law Firm

1995 - 2012

  • 2022 Shortlisted for Women in Law Mena Region Award LexisNexis.
Dr. Zubair Shah

Dr. Zubair Shah

Assistant Professor

Office location

A-101F

Dr. Zubair Shah

Assistant Professor

Educational Qualifications

PhD in Data Science

MSc in Computer System Engineering

Entity

College of Science and Engineering

Division

Information & Computing Technology

Biography

Dr. Zubair Shah is an Assistant Professor in the College of Science and Engineering specializing in artificial intelligence and big data analytics with a focus on health informatics. He holds an MS degree in Computer System Engineering from Politecnico di Milano, Italy, and a PhD from the University of New South Wales, Australia. Before joining HBKU, Dr. Shah was a Research Fellow at the Australian Institute of Health Innovation, Macquarie University, from 2017 to 2019.

Dr. Shah's research focuses on applying AI to healthcare, particularly in developing AI-driven applications that enhance disease diagnosis and prediction. He has secured critical funding from HBKU Innovation Center and QNRF to advance these efforts, including work on diabetes management and multimodal AI systems combining electronic health records (EHR), medical imaging, and multi-omics data. His team has developed innovative deep-learning techniques, including methods for identifying IDH mutations from histopathology slides and exploring the use of generative models like GANs and neural diffusion for medical data augmentation.

Dr. Shah has published extensively in leading international journals and conferences, and his research also explores the potential of foundation AI models in healthcare, contributing significantly to advancements in AI-powered medical diagnostics.

PhD in Data Science

University of New South Wales, Australia

2017

MSc in Computer System Engineering

Politecnico Di Milano, Italy

2011

BS in Computer Science

University of Peshawar, Pakistan

2005

  • Digital Epidemiology and behavioral analysis of vaccination attitudes
  • AI-driven healthcare applications
  • Deep learning in medical imaging
  • Generative models for medical data

Assistant Professor

College of Science and Engineering, Hamad Bin Khalifa University

2019 - Present

Research Fellow

Australian Institute of Health Innovation, Macquarie University, Australia

2017 - 2019

Lecturer

Computer Science, City University of Science and Information Technology, Pakistan

2012 - 2013

System Engineer

National Database and Registration Authority, Pakistan

2006 - 2009

Mohsen, F., Al-Absi, H. R. H., Yousri, N. A., El Hajj, N., & Shah, Z. (2023). A scoping review of artificial intelligence-based methods for diabetes risk prediction. NPJ Digital Medicine, 6(1), 197.

Mohsen, F., Ali, H., El Hajj, N., & Shah, Z. (2022). Artificial intelligence-based methods for fusion of electronic health records and imaging data. Scientific Reports, 12(1), 17981.

Ahmad, W., Ali, H., Shah, Z., & Azmat, S. (2022). A new generative adversarial network for medical images super resolution. Scientific Reports, 12(1), 1–20.

Shah, U., Biswas, M. R., Ali, R., Ali, H., & Shah, Z. (2022). Public attitudes on social media toward vaccination before and during the COVID-19 pandemic. Human Vaccines & Immunotherapeutics, 18(6), 2101835.

Liu, S., Shah, Z., Sav, A., Russo, C., Berkovsky, S., Qian, Y., Coiera, E., & Di Ieva, A. (2020). Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning. Scientific Reports, 10(1), 7733.

  • 2016 Postgraduate Research Student Support (PRSS), UNSW, Australia
  • 2014 University College Postgraduate Research Scholarship (UCPRS), UNSW, Australia
  • 2009 DSU-International Postgraduate Scholarship, Politecnico di Milano, Italy
  • 2005 Distinction at Department of Computer Science, University of Peshawar, Pakistan 
Dr. Afif Ben Mahmoud

Dr. Afif Ben Mahmoud

Senior Research Associate

Office location

C142 / RC-B2-1127

Dr. Afif Ben Mahmoud

Senior Research Associate

Educational Qualifications

PhD (Molecular and Human Genetics)

MSc in Genetics and Biodiversity

Entity

Qatar Biomedical Research Institute

Division

Neurological Disorders Research Center

Biography

Dr. Afif Ben Mahmoud is an accomplished geneticist and genome data analyst with extensive expertise in human molecular genetics. He earned an engineering degree in agriculture and animal production, a master's in genetics and biodiversity, and a PhD in molecular and human genetics. With over 12 years of experience in research and academia, Dr. Ben-Mahmoud has dedicated his work to elucidating cellular and molecular mechanisms underlying human genetic diseases, focusing on identifying disease genes and mutations responsible for rare recessive disorders, particularly in Arab populations.

His professional contributions in genetic pathology span from phenotypic and genotypic characterization of patients with monogenic diseases to functional studies aimed at demonstrating the pathogenicity of disease-causing novel genes and gene variations. He has also led numerous projects to decode rare human monogenic diseases, significantly advancing the field. 


Dr. Afif Ben Mahmoud’s notable accomplishments include the first functional analysis of B3GALTL in Tunisian patients with Peters Plus Syndrome, the identification of MAST1 as a novel intellectual disability gene, and confirming the role of B3GALT6 in Al-Gazali Syndrome. Additionally, he has identified 16 autosomal dominant candidate genes in syndromic neurodevelopmental disorders and new candidate loci for intellectual disability and Kallmann syndrome. Dr. Ben-Mahmoud has published 25 high-quality articles in renowned international peer-reviewed journals, with over 500 citations and an h-index of 14.

PhD (Molecular and Human Genetics)

Sfax University, Tunisia

2015

MSc in Genetics and Biodiversity

Monastir University, Tunisia

2009

Engineering in Agriculture and Animal Production

Carthage University, Tunisia

2007

  • Identification of novel disease genes and their pathogenic variants in autism and human monogenic diseases in Qatar.
  • Investigation of genetic diversity and recessive disorders in Arab populations in Qatar.
  • Functional validation of novel genes associated with intellectual disability and autism spectrum disorder in the Qatari population.
  • Elucidation of cellular and molecular mechanisms in syndromic neurodevelopmental disorders in Qatar.

Senior Research Associate

Qatar Biomedical Research Institute, Hamad Bin Khalifa University

2019 - present

PostDoc Researcher

College of Medicine & Health Sciences, United Arab Emirates University, UAE

2016 - 2018

Ben-Mahmoud, A., Kishikawa, S., Gupta, V., Leach, N. T., Shen, Y., Moldovan, O., Goel, H., Hopper, B., Ranguin, K., Gruchy, N., Maas, S. M., Lacassie, Y., Kim, S. H., Kim, W. Y., Quade, B. J., Morton, C. C., Kim, C. H., Layman, L. C., & Kim, H. G. (2023). A cryptic microdeletion del(12)(p11.21p11.23) within an unbalanced translocation t(7;12)(q21.13;q23.1) implicates new candidate loci for intellectual disability and Kallmann syndrome. Scientific Reports, 13(1), Article 12984.

Ben-Mahmoud, A., Gupta, V., Kim, C.-H., Layman, L. C., & Kim, H.-G. (2023). Digenic or oligogenic mutations in presumed monogenic disorders: A review. Journal of Genetic Medicine, 20(1), 15–24.

Ben-Mahmoud, A., Jun, K. R., Gupta, V., Shastri, P., de la Fuente, A., Park, Y., Shin, K. C., Kim, C. A., da Cruz, A. D., Pinto, I. P., Minasi, L. B., Silva da Cruz, A., Faivre, L., Callier, P., Racine, C., Layman, L. C., Kong, I. K., Kim, C. H., Kim, W. Y., & Kim, H. G. (2022). A rigorous in silico genomic interrogation at 1p13.3 reveals 16 autosomal dominant candidate genes in syndromic neurodevelopmental disorders. Frontiers in Molecular Neuroscience, 15, Article 979061.

Ben-Mahmoud, A., Al-Shamsi, A. M., Ali, B. R., & Al-Gazali, L. (2020). Evaluating the role of MAST1 as an intellectual disability disease gene: Identification of a novel de novo variant in a patient with developmental disabilities. Journal of Molecular Neuroscience, 70(3), 320–327.

Ben-Mahmoud, A., Ben-Salem, S., Al-Sorkhy, M., John, A., Ali, B. R., & Al-Gazali, L. (2018). A B3GALT6 variant in a patient originally described as Al-Gazali syndrome and implicating the endoplasmic reticulum quality control in the mechanism of some β3GalT6-pathy mutations. Clinical Genetics, 93(6), 1148–1158.

  • 2018; Researchers at UAEU develop cell lines with gene-editing technology CRISPR-Cas9 used to understand diseases
Dr. Nehad Alajez

Dr. Nehad Alajez

Principal Investigator

Joint Professor

Dr. Nehad Alajez

Principal Investigator

Joint Professor

Educational Qualifications

PhD

MSc

Entity

Qatar Biomedical Research Institute

College of Health and Life Sciences

Division

Translational Oncology Research Center

Biography

Dr. Nehad Alajez earned his PhD in tumour immunology from the University of Pittsburgh School of Medicine in USA, and subsequently completed his post-doctoral training at the Princess Margaret Cancer Center (University Health Network), a premier cancer research institute in Canada. His main research interest is to investigate the role of the Polycomb gene family and non-coding microRNAs in driving cancer progression and their potential utilization for targeted therapies. Dr. Alajez is a recipient of several prestigious awards and has published more than 100 articles in top-tier ISI-indexed journals including Blood, Cancer Research, Cell Death and Differentiation, Cell Death and Disease, Signal Transduction and Targeted Therapy, Molecular Therapy (family journals), EMBO Molecular Medicine, and in Science Translational Medicine. Dr. Alajez currently has close to 5000 citations and an h-index of 35 and i10-index of 74.

Prior to his current appointment, Dr. Alajez was appointed as the Associate Professor at King Saud University College of Medicine, Kingdom of Saudi Arabia. Dr. Alajez’s main research interests are focused on ‘translational oncology research’ with main emphasis on novel biomarker discovery and targeted therapeutics for breast cancers. In particular, Dr. Alajez’s team is studying noncoding RNAs (micoRNAs and lncRNAs) as disease and predictive biomarkers for patients’ response to therapy. Dr. Alajez has strong expertise in transcriptome analysis, noncoding RNAs, and biomarker discovery field and is currently ranked among the top 2% most cited scientist globally. He is a recipient of several major grants, including funding from Qatar National Research Fund, in addition to his editorial roles on several journals.

 

PhD

University of Pittsburgh, USA

2003

MSc

San Francisco State University, USA

1999

BSc

Islamic University of Gaza, Palestine

1995

Dr. Alajez main research interests are focused on precision medicine aiming at the discovery of novel tumour and circulating biomarkers for breast cancer diagnosis, prognosis, and therapy. Additionally, Dr. Alajez’s group is conducting CRISPR-Cas9 genomic screens to elucidate the role of miRNAs and lncRNAs in driving breast cancer survival and resistance to standard therapies.

  • Identification of molecular signatures predictive of pathological complete response to neoadjuvant therapy in breast cancer.
  • Identification of circulating miRNAs as diagnostic and predictive biomarkers for breast cancer.
  • Transcriptomic profiling of breast cancer for diagnostic
  • prognostic
  • and therapeutic applications.
  • CRISPR-Cas9 genomic screen to identify novel therapeutic vulnerabilities in breast cancer.

Principal Investigator

Translational Oncology Research Center, Qatar Biomedical Research Institute

2022 - Present

Senior Scientist

Translational Cancer and Immunity Center, Qatar Biomedical Research Institute

2018 - 2022

Associate Professor

College of Medicine, King Saud University

2015 - 2018

Assistant Professor

College of Medicine, King Saud University

2011 - 2015

Vishnubalaji R, Shaath H, Al-Alwan M, Abdelalim EM, Alajez NM. Reciprocal interplays between MicroRNAs and pluripotency transcription factors in dictating stemness features in human cancers. Semin Cancer Biol 2022;87:1-16.

Vishnubalaji R, Abdel-Razeq H, Gehani S, Albagha OME, Alajez NM. Identification of a Gene Panel Predictive of Triple-Negative Breast Cancer Response to Neoadjuvant Chemotherapy Employing Transcriptomic and Functional Validation. Int J Mol Sci 2022;23(18).

Shaath H, Vishnubalaji R, Elango R, Kardousha A, Islam Z, Qureshi R, et al. Long non-coding RNA and RNA-binding protein interactions in cancer: Experimental and machine learning approaches. Semin Cancer Biol 2022;86(Pt 3):325-45.

Vishnubalaji R, Alajez NM. Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq. Mol Ther Oncolytics 2021;23:151-62.

Shaath H, Vishnubalaji R, Elango R, Khattak S, Alajez NM. Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy. Cell Death Discov 2021;7(1):23.

Elango R, Vishnubalaji R, Shaath H, Alajez NM. Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel. Mol Ther Methods Clin Dev 2021;20:601-14.

Alajez NM. COVID-19: complexity of disease severity revealed by systemic and localized single cell immune atlas. Signal Transduct Target Ther 2021;6(1):156.

Vishnubalaji R, Shaath H, Elango R, Alajez NM. Noncoding RNAs as potential mediators of resistance to cancer immunotherapy. Semin Cancer Biol 2020;65:65-79.

Shaath H, Vishnubalaji R, Elkord E, Alajez NM. Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19. Cells 2020;9(11).

Sasidharan Nair V, Toor SM, Taouk G, Pfister G, Ouararhni K, Alajez NM, et al. Pembrolizumab Interferes with the Differentiation of Human FOXP3(+)-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR. J Immunol 2020;204(1):199-211.

Hanieh H, Ahmed EA, Vishnubalaji R, Alajez NM. SOX4: Epigenetic regulation and role in tumorigenesis. Semin Cancer Biol 2020;67(Pt 1):91-104.

Elango R, Alsaleh KA, Vishnubalaji R, Manikandan M, Ali AM, Abd El-Aziz N, et al. MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM. Front Oncol 2020;10:756.

Vishnubalaji R, Shaath H, Elkord E, Alajez NM. Long non-coding RNA (lncRNA) transcriptional landscape in breast cancer identifies LINC01614 as non-favorable prognostic biomarker regulated by TGFbeta and focal adhesion kinase (FAK) signaling. Cell Death Discov 2019;5:109

Vishnubalaji R, Elango R, Al-Toub M, Manikandan M, Al-Rikabi A, Harkness L, et al. Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B. Sci Rep 2019;9(1):8101

Elango R, Vishnubalaji R, Manikandan M, Binhamdan SI, Siyal AA, Alshawakir YA, et al. Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo. Sci Rep 2019;9(1):13696

Hamam R, Hamam D, Alsaleh KA, Kassem M, Zaher W, Alfayez M, et al. Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers. Cell Death Dis 2017;8(9):e3045

Vishnubalaji R, Hamam R, Yue S, Al-Obeed O, Kassem M, Liu FF, et al. MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1. Oncotarget 2016;7(24):35789-802.

Hamam R, Ali AM, Alsaleh KA, Kassem M, Alfayez M, Aldahmash A, et al. microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection. Sci Rep 2016;6:25997.

Vishnubalaji R, Hamam R, Abdulla MH, Mohammed MA, Kassem M, Al-Obeed O, et al. Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer. Cell Death Dis 2015;6(1):e1614.

Ito E, Yue S, Moriyama EH, Hui AB, Kim I, Shi W, et al. Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer. Sci Transl Med 2011;3(67):67ra7.

Alajez NM, Lenarduzzi M, Ito E, Hui AB, Shi W, Bruce J, et al. MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res 2011;71(6):2381-91.

Alajez NM, Shi W, Hui AB, Yue S, Ng R, Lo KW, et al. Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy. Cell Death Differ 2009;16(11):1469-79.

Alajez NM, Schmielau J, Alter MD, Cascio M, Finn OJ. Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution. Blood 2005;105(12):4583-9.

  • 2022, Qatar Biomedical Research Institute top publishing.
  • 2022, Qatar Biomedical Research Institute top external received funding.
  • 2022, among top 2% most cited scientists worldwide.
  • 2021, among top 2% most cited scientists worldwide.
  • 2021, Qatar Biomedical Research Institute highest publication award.
  • 2010, Scholar-in-Training Award, American Association of Cancer Research.
  • 2007, Excellence in Radiation Research for the 21st Century Award, Canadian Institute for Health Research.
  • 2004, Scholar-in-Training Award, American Association of cancer research.
  • 2001, DOD pre-doctoral training Award on Breast Cancer Research.
  • 1999, San Francisco State University distinguished achievement award for academic excellence.
  • 1997, Fulbright Scholarship.