adjunct

Dr. Nayef Mazloum

Dr. Nayef Mazloum

Adjunct Associate Professor

Office location

C014, South Hall, WCM-Q

Dr. Nayef Mazloum

Adjunct Associate Professor

Educational Qualifications

PhD in Biochemistry and Molecular Biology

BS in Biology

Entity

College of Health and Life Sciences

Biography

Dr. Nayef A. Mazloum is an Adjunct Associate Professor at Hamad Bin Khalifa University. He graduated from the American University of Beirut in 1994 and completed his PhD in biochemistry and molecular biology at New York Medical College in Valhalla in 2003.

Dr. Nayef A. Mazloum worked as an instructor of microbiology and immunology at Weill Cornell Medical College in New York. He did his postdoctoral training at Memorial Sloan Kettering Cancer Center and worked at Weill Cornell Medicine-Qatar (WCM-Q).

Dr. Mazloum’s research focuses on the molecular aspects of DNA repair mechanisms, the stability of the genome, and how the dysfunction of these regulatory pathways could lead to cancer, age-related or metabolic diseases.

His lab employs cellular, molecular, and genetic tools to investigate altered molecular pathways in metabolic disorders and cancer. Dr. Mazloum actively collaborates with local stakeholders in Qatar, including Hamad Medical Corporation, Qatar University, Texas A&M University, Qatar Biomedical Research Institute, and Hamad Bin Khalifa University. He also collaborates with global investigators at Harvard Medical School, Mayo Clinic, Brown University, and the University of East Anglia.

PhD in Biochemistry and Molecular Biology

New York Medical College, Valhalla, United States

2003

BS in Biology

American University of Beirut, Lebanon

1994

  • Function of Sirt1 in adipocyte proliferation and differentiation
  • Molecular mechanisms regulated by the oncogene C-Myc
  • Mechanisms of cellular senescence in Obesity and Diabetes
  • Function of the E3 ubiquitin-protein Ligase UHRF1

Adjunct Associate Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2025 - Present

Associate Professor of Microbiology and Immunology

Research, Weill Cornell Medicine Qatar

2024 - Present

Assistant Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2015 - 2025

Assistant Dean for Student Research

Weill Cornell Medicine Qatar, Weill Cornell Medicine Qatar

2017 - Present

Assistant Professor of Microbiology and Immunology

Research, Weill Cornell Medicine Qatar

2011 - 2024

Instructor

Microbiology and Immunology, Weill Cornell Medicine New York, United States

2008 - 2010

Postdoctoral Research Associate

Microbiology and Immunology, Weill Cornell Medicine New York, United States

2004 - 2010

Vakayil, M., Madani, A. Y., Agha, M. V., Majeed, Y., Hayat, S., Yonuskunju, S., Mohamoud, Y. A., Malek, J., Suhre, K., & Mazloum, N. A. (2024). The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling. Scientific Reports, 14(1), 11886.

Majeed, Y., Madani, A. Y., Altamimi, A. I., Courjaret, R., Vakayil, M., Fountain, S. J., Machaca, K., & Mazloum, N. A. (2023). STAT1- and NFAT-independent amplification of purinoceptor function integrates cellular senescence with interleukin-6 production in preadipocytes. British Journal of Pharmacology, 180(5), 609–627.

Majeed, Y., Halabi, N., Madani, A. Y., Engelke, R., Bhagwat, A. M., Abdesselem, H., Agha, M. V., Vakayil, M., Courjaret, R., Goswami, N., Hamidane, H. B., Elrayess, M. A., Rafii, A., Graumann, J., Schmidt, F., & Mazloum, N. A. (2021). SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways. Scientific Reports, 11(1), 8177.

Madani, A. Y., Majeed, Y., Abdesselem, H. B., Agha, M. V., Vakayil, M., Sukhun, N. K. A., Halabi, N. M., Kumar, P., Hayat, S., Elrayess, M. A., Rafii, A., Suhre, K., & Mazloum, N. A. (2021). Signal Transducer and Activator of Transcription 3 (STAT3) suppresses STAT1/interferon signaling pathway and inflammation in senescent preadipocytes. Antioxidants, 10(2), 1–25.

Al-Sulaiti, H., Diboun, I., Agha, M. V., Mohamed, F. F. S., Atkin, S., Dömling, A. S., Elrayess, M. A., & Mazloum, N. A. (2019). Metabolic signature of obesity-associated insulin resistance and type 2 diabetes. Journal of Translational Medicine, 17(1), 348.

Complete Publication Listing(s): PubMed

  • 2000; First Prize Winner, Annual Graduate Student Research Forum, NYMC.
  • 1991; Harriri Foundation Scholarship Award, AUB.

Dr. Said Dermime

Adjunct Associate Professor

Dr. Said Dermime

Adjunct Associate Professor

Educational Qualifications

Biochemistry (Major)

MSc. Immunology/Biochemistry

Entity

College of Health and Life Sciences

Biography

Dr. Said Dermime obtained his PhD degree in immunology from Salford University, Manchester, UK in 1992. In 2015, Dr. Said joined NCCCR at HMC, Doha, Qatar as a director of the Translational Cancer Research Facility. Dr. Said Dermime is an adjunct associate professor at Hamad Bin Khalifa. He is also a mentor supervisor of PhD/master’s programs; he supervised 3 PhD and 2 master’s students.

Dr. Said published over 88 peer-reviewed articles in high impact factor journals. He also published several Book Chapters in prestigious publishers and is an editor/reviewer for many prestigious international scientific journals. Dr Said’s most prominent work includes identifying the cause of resistance to the drug retinoic acid in acute leukemia, discovering a novel leukemia vaccine against proteinase-3 as a target antigen and demonstrating that the lymphoma idiotype is a potential cancer vaccine target. He has also demonstrated, for the first time, the expression of the PD-L1 inhibitory molecule in breast cancer patients, showed direct evidence of PD-L1 induction in breast cancer cells and the involvement of both PD-L1 and regulatory T cells in the immune escape of breast cancer.

In addition, he was able to discover an antigen-specific regulatory T cell population in leukemia patients. Recently, he was able to demonstrate that the presence of anti-NY-ESO-1 integrated immunity and a specific cytokines/chemokines profile may potentially identify a response to PD-1 blockade in head and neck squamous cell carcinoma (HNSCC) patients. He was also able to show that a patient with metastatic gastric cancer benefiting from combined radio-immunotherapy treatment possesses persistent anti-NY-ESO-1 specific T cells and expresses differential biomarkers. 

 

Biochemistry (Major)

Department of Biological Sciences, University of Constantine, Constantine, Algeria

1981 - 1985

MSc. Immunology/Biochemistry

Department of Biological Sciences, University of Salford, Manchester, UK

1986 - 1988

PhD. Immunology/Microbiology (Supervisor: Dr John Alexander)

Department of Biological Sciences, University of Salford, Manchester, UK

1989 - 1992

  • Designing therapeutic
  • prophylactic strategies and evaluating them in preclinical and clinical studies. This is to develop complementary approaches for immunological assays of tumor immunity and cancer vaccines.

Associate Professor

College of Health and Life Sciences (CHLS), Hamad Bin Khalifa University, Doha, Qatar

Sep 2018 - Present

Senior Scientist and Director of Translational Cancer Research Facility

Interim Translational Research Institute (iTRI), Hamad Medical Corporation, Doha, Qatar

Sep 2015 - Present

Senior Principal Scientist/Head of Immunology & Cell Therapy and Director of Biomedical Research Facility

King Fahad Specialist Hospital, Dammam, KSA

Oct 2012 - May 2015

Senior Scientist/Head of Immunology & Innovative Cell Therapy Unit

Department of Biomedical Research, Dasman Diabetes Institute, Dasman, Kuwait

Oct 2008 - Oct 2012

Senior Scientist/Head of the Tumor Immunology Unit

Department of Biological & Medical Research, King Faisal Specialist Hospital and Research Centre, Riyadh, KSA

Dec 2002 - Oct 2008

Senior Scientist/Team Leader of a Lymphoma Vaccine

Department of Medical Oncology/Immunology, Paterson Institute for Cancer Research, Christie Hospital and University of Manchester, Manchester, UK

Sep 1998 - Dec 2002

Senior Research Immunologist

Cobra Therapeutics Ltd., Staffordshire, UK

Dec 1997 - Sep 1998

Mestiri, Sarra; Merhi, Maysaloun; Inchakalody, Varghese; Taib, Nassiba; Smatti, Maria; Ahmad, Fareed; Raza, Afsheen; Ali, Fatma; Hydrose, Shereena; Fernandes, Queenie; Ansari, Abdul; Sahir, Fairooz; Al-Zaidan, Lobna; Jalis, Munir; Ghoul, Mokhtar; Allahverdi, Niloofar; Homsi, Mohammed; Uddin, Shahab; Jeremijenko, Andrew; Dermime, Said. (2023). Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study. Frontiers in Immunology. 14. 10.3389/fimmu.2023.1061255 (Impact Factor 8.78).

Maalej, Karama; Merhi, Maysaloun; Inchakalody, Varghese; Mestiri, Sarra; Alam, Majid; Maccalli, Cristina; Cherif, Honar; Uddin, Shahab; Steinhoff, Martin; Marincola, Francesco; Dermime, Said. (2023). CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances. Molecular Cancer. 22. 10.1186/s12943-023-01723-z (Impact Factor 41.4).

Raza, Afsheen; Bourouba, Mehdi; Dermime, Said. (2023). Editorial: Genomics, proteomics and immunological signatures as diagnostic, predictive, and prognostic biomarkers in head and neck cancers. Frontiers in Immunology. 14. 10.3389/fimmu.2023.1122736 (Impact Factor 8.78).

Akbar, Shayista; Raza, Afsheen; Mohsin, Reyad; Kanbour, Aladdin; Qadri, Shahnaz; Parray, Aijaz; Gul, Abdul; Philip, Anite; Vijayakumar, Suma; Merhi, Maysaloun; Hydrose, Shereena; Inchakalody, Varghese; Al-Abdulla, Rajaa; Abualainin, Wafa; Sirriya, Shaza; Al-Bozom, Issam; Uddin, Shahab; Khan, Omar; Mohamed Ibrahim, Mohamed Izham; Dermime, Said. (2023). Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients. Frontiers in Immunology.13.10.3389/fimmu.2022.1097117 (Impact Factor 8.78).

Mohsen, Mona O; Speiser, Daniel; Michaux, Justine; Pak, HuiSong; Stevenson, Brian; Vogel, Monique; Inchakalody, Varghese; Brot, Simone; Dermime, Said; Coukos, Georges; Bassani, Michal; Bachmann, Martin. (2022). Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma. Journal for ImmunoTherapy of Cancer. 10. e002927. 10.1136/jitc-2021-002927 (Impact Factor 12.49).

  •  Award by the Algerian High Education Ministry to carry out an MSc program at University of Salford, Manchester, UK, Department of Biological Sciences, MSc–Immunology/Biochemistry (Supervisor: Dr John Alexander)
  • Award by the Algerian High Education Ministry to carry out a PhD program at University of Salford, Manchester, UK , Department of Biological Sciences PhD–Immunology/Microbiology (Supervisor: Dr John Alexander)
  • Award by the International Fogarty, USA to carry out a fellowship program at National Institutes of Health, Bethesda MD, USA, National Heart, Lung and Blood Institute, Bone Marrow Transplantation Unit, Hematology Branch, Visiting Research Fellow, Tumor Immunology/Hematology (Prof John Barrett)
Dr. Martin Steinhoff

Dr. Martin Steinhoff

Professor

Office location

00974 44395101

Dr. Martin Steinhoff

Professor

Educational Qualifications

PhD in Human Biology

MD Medicine Thesis

Entity

College of Health and Life Sciences

Biography

Professor Martin Steinhoff is a Professor at Hamad Bin Khalifa University. He is also the Chairman of the Department of Dermatology and Venereology, Director of the Dermatology Institute, and Director of the Translational Research Institute (TRI) at Hamad Medical Corporation (HMC). He is also a Full Professor at Weill Cornell Medical College New York, USA, Weill-Cornell Medicine-Qatar, and Qatar University. He also holds the position of residency program director for dermatology at HMC.

Professor Steinhoff studied medicine and human biology in Germany, where he received his MD, M.Sc., and PhD from the University of Marburg. After his residency in Dermatology/Venereology, he became an Assistant Professor of Dermatology at the University of Muenster in 2002, promoted from assistant to full professor in 6 years.

He holds board certificates in Dermatology, Venereology, Phlebology and Allergy. His clinical fields of interest are inflammatory skin diseases, translational medicine, and -omics technologies. Prof. Steinhoff is an established physician-scientist with a long-standing basic and clinical research background. His group has discovered several mechanisms that are now the basis for new therapies for skin diseases. He is the author of the most relevant textbooks for Dermatology on Skin Inflammation and Allergy.

For his research, Prof Steinhoff received several prestigious international research awards worldwide. He was a member of the board of directors of the European Society of Dermatology Research (ESDR) and an honorary member of several Societies for Dermatology. According to a publication in 2023, he was considered among the Top 1% of dermatologists worldwide.

PhD in Human Biology

University of Marburg, Germany

1997 - 2001

MD Medicine Thesis

University of Marburg, Germany

1986 - 1994

MSc in Human-Biology

University of Marburg, Germany

1990 - 1992

BSc in Biology

Technical University of Braunschweig, Germany

1983 - 1986

  • Neuroimmunology
  • Atopic Dermatitis
  • Psoriasis
  • Rosacea
  • Systems Medicine
  • Cell signaling
  • Identification of disease biomarkers
  • and new therapies

Director

Translational Research, Hamad Medical Corporation

2017 - Present

Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2016 - Present

Chairman

Dermatology, Venerology, Allergy, Hamad Medical Corporation

2016 - Present

Chairman and Director

Dermatology, University College Dublin, Ireland

2014 - 2016

Full Professor

Dermatology, University of California San Francisco, United States

2009 - 2013

Associate Professor

Dermatology, University of Muenster, Germany

2005 - 2011

Assistant Professor

Dermatology, University of Muenster, Germany

2003 - 2005

Scientific University Assistant

Dermatology, University of Muenster, Germany

1999 - 2003

Postdoc (MD)

Neurosciences, Cell Biology, University of California San Francisco, United States

1997 - 1999

AiP & Resident

Dermatology, Venerology, Allergy, University of Goettingen, Germany

1995 - 1997

Postgraduate clinical training (AiP)

Internal Medicine, University of Marburg, Germany

1995

Steinhoff, M., Szabo, I., Schmelz, M., & Oaklander, A. L. (2018). Neuropathic itch. The Lancet Neurology, 17(8), 709–720.

Kido-Nakahara, M., Buddenkotte, J., Kempkes, C., Ikoma, A., Cevikbas, F., Akiyama, T., Nunes, F., Seeliger, S., Hasdemir, B., Mess, C., Buhl, T., Sulk, M., Müller, F.-U., Metze, D., Bunnett, N. W., Bhargava, A., Carstens, E., Furue, M., & Steinhoff, M. (2014). Neural peptidase endothelin-converting enzyme-1 regulates endothelin-1-induced pruritus. Journal of Clinical Investigation, 124(6), 2683–2695.

Cevikbas, F., Wang, X., Akiyama, T., Kempkes, C., Savinko, T., Antal, A., Kukova, G., Buhl, T., Ikoma, A., Buddenkotte, J., Soumelis, V., Feld, M., Alenius, H., Dillon, S. R., Carstens, E., Homey, B., Basbaum, A., & Steinhoff, M. (2014). A sensory neuron-expressed interleukin-31 receptor mediates T-helper cell-dependent itch: Involvement of TRPV1 and TRPA1. Journal of Allergy and Clinical Immunology, 133(2), 448–460.e7.

Affara, N. I., Ruffell, B., Medler, T. R., Gunderson, A. J., Johansson, M., Bornstein, S., Bergsland, E., Steinhoff, M., Li, Y., Gong, Q., Ma, Y., Wiesen, J. F., Wong, M. H., Kulesz-Martin, M., Irving, B., & Coussens, L. M. (2014). B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas. Cancer Cell, 25(6), 809–821.

Steinhoff, M., Vergnolle, N., Young, S. H., Tognetto, M., Amadesi, S., Ennes, H. S., Trevisani, M., Hollenberg, M. D., Wallace, J. L., Caughey, G. H., Mitchell, S. E., Williams, L. M., Geppetti, P., Mayer, E. A., & Bunnett, N. W. (2000). Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nature Medicine, 6(2), 151–158.

  • 2024; Qatar Foundation QNRF Award Precision Medicine Research, 3 years.
  • 2016; SFI-Pfizer Innovation Research Award from Minister of Health, Ireland (Development of biologic) Science Foundation Ireland
  • 2011; NIH R01 Research Award, NIAMS (5 years. 3 Mio US $ with overhead), P.I. 8th percentile.
  • 2001; Oskar-Gans Main research award, German Society of Dermatology, Berlin, Germany, May 5, 2001 (Protease-activated receptors and neuroinflammation and pruritus).
  • 1997; NIH-Scholarship (University of California, San Francisco, CA, USA (Depts. of Physiology & Surgery, Prof. Dr. N. Bunnett), 3 years, NIH grant.
Dr. Sahar Isa Da’as

Dr. Sahar Isa Da’as

Assistant Professor

Office location

Sidra Medicine OPC - C6-73031-D01

Dr. Sahar Isa Da’as

Assistant Professor

Educational Qualifications

PhD in Biomedical and Biological Sciences

MSc in Applied Biological Sciences

Entity

College of Health and Life Sciences

Biography

Sahar Isa Da’as is a distinguished research manager at Sidra Medicine and an assistant professor at Hamad Bin Khalifa University. Her research is centered on functional genomics and translational research. She has worked at IWK Health Centre in Canada, focusing on rare genetic disorders and childhood cancers. She was also awarded the Innovation Excellence Award from Cancer Care Nova Scotia Health Authority.

Dr. Da'as has pioneered innovative approaches using the zebrafish model, focusing on rare pediatric hereditary diseases. She has successfully developed patient-specific genotype models, providing a comprehensive insight into gene variation, clinical presentations, and disease prognosis. This achievement promises a roadmap toward precision medicine and underscores her dedication to advancing healthcare through cutting-edge research.

Through collaborative projects, Dr Da'as continues translating scientific discoveries into practical applications, providing a foundation for translational studies of novel genes and variants. Her work is published in many reputable journals and has significantly advanced the understanding of hereditary diseases.

PhD in Biomedical and Biological Sciences

Hamad Bin Khalifa University, Qatar

2019

MSc in Applied Biological Sciences

Jordan University of Science and Technology, Jordan

1999

BSc in Biological Sciences

University of Jordan, Jordan

1996

  • Rare hereditary pediatric disease modeling
  • Genetics and functional characterization of neurological disorders
  • Genetics and functional characterization of cardiovascular diseases

Assistant Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2024 - Present

Research Manager

Research Department, Sidra Medicine

2013

Laboratory Manager

Weill Cornell Medical College, Qatar

2012 - 2013

Laboratory Manager

Pediatrics Department, IWK Health Centre, Canada

2007 - 2012

  • 2022; Top author – Core Facilities Category, Sidra Medicine, Qatar
  • 2015; THANAA Award- Qatar Foundation Professional Excellence Award. Doha, Qatar
  • 2014; THANAA Award- Qatar Foundation Professional Excellence Award. Doha, Qatar
  • 2012; Innovation Excellence Award – Cancer Care Nova Scotia Excellence Awards, Canada
  • 2012; IWK STARS Team Recognition Award – IWK Health Centre, Halifax, Canada
Said Ismail

Dr. Said Ismail

Adjunct Professor

Office location

QSTP, IC building, room 354

Dr. Said Ismail

Adjunct Professor

Educational Qualifications

Ph.D.

M.Sc.

Entity

College of Health and Life Sciences

Biography

Dr. Said Ismail is the director of the Qatar Genome Programme (QGP), one of the major national programs in the region. He obtained his Doctor of Philosophy (PhD) from the University of Oxford and has work experience extending into various fields including research, education, and consultancy. 

As a research fellow at University College London (UCL), Dr. Ismail served as a consultant to several regional and international pharma and biotech companies. 

Dr. Ismail is especially interested in promoting research among young students and researchers in the Arab world. He launched one of the largest efforts to enhance the Arabic medical and scientific content on the internet; The “Bel-Arabi” or “In- Arabic” initiative. He is also a board member of the Phi Science Institute, which aims to spread creative sciences and research among youth.

 

Ph.D.

University of Oxford, UK, (10/97-8/2000): Gene Therapy

M.Sc.

University College London, UK, (9/1995-9/1996): Applied Molecular Biology and Biotechnology

B.Sc.

University of Jordan, Jordan (1/1991-1/1995): Medical Laboratories Technology

  • Cancer Genetics and Targeted Therapeutics
  • Genomics and Precision Medicine

Director

Qatar Genome Program, Qatar Foundation

2015 - present

Adjunct Professor

College of Health and Life Sciences, Hamad Bin Khalifa University (HBKU), Qatar Foundation

2017 - present

Professor of Molecular Biology

Medical School, University of Jordan

2002 - 2015

Head, Biochemistry and Physiology Department,

Medical School, University of Jordan

2014 - 2015

Head, Molecular Biology Research Laboratory

Faculty of Medicine University of Jordan

2005 - 2015

Managing director

Molecular Diagnostics Reference Lab, University of Jordan Hospital

2008 - 2015

Research Fellow

Ludwig Institute for Cancer Research, University College London, UK

2000 - 2002

Split-intron retroviral vectors; Enhanced expression and improved safety. Journal of Virology, 2000. 74:2365-2371.

Use of intron disrupted polyadenylation sites to enhance expression and safety of retroviral vectors. Journal of Virology, 2001. 75: 199-204.

Transcriptional Networks and Cellular Senescence in Human Mammary Fibroblasts. Molecular Biology of the Cell, 2005. Vol. 16, Issue 2, 943-953.

Molecular Heterogeneity of glucose 6 phosphate dehydrogenase (G6PD) deficiency in Jordan. Haematologica, 2005. Dec; 90(12): 1693-4.

Highly sensitive multiplex RT-PCR system for the detection of all common BCR-ABL transcripts. Jordan Medical Journal, 2006, 41(2): 96-104.

Identification of atypical PML-RARA breakpoint in a patient with acute promyelocytic leukemia. Acta Haematologica, 2007, 118:183-187.

Successful Bone Marrow Transplantation for Treatment of Chronic Myeloid Leukemia from a Donor with Mosaic Klinefelter Syndrome. International Journal of Hematology, 2007, 86(3): 287-288.

The Transforming Mutation E17K/AKT1 is not a Major Event in B-Cell Derived Lymphoid Leukaemias. British Journal of Cancer, 2008, 99: 488–490.

Methylenetetrahydrofolate Reductase (MTHFR) genotype association with the risk of Chronic Myelogenous Leukemia. Jordan Medical Journal, 2009, 43(1):8-13.

Screening patients with polycythemia vera for c-Kit mutations. Leukemia & Lymphoma, 2009; 50(1): 127–129.

Detection of combined genomic variants in a Jordanian family with familial non autoimmune hyperthyroidism. Journal of Genetics, 2009, 88(2): 233-238.

Methylenetetrahydrofolate Reductase (MTHFR) Genotype Association With the Risk of Follicular Lymphoma. Cancer Genetics and Cytogenetics. 2009, 195(2); 120-124

Frequency of t(14;18) in follicular lymphoma patients: Geographical or technical variation. International Journal of Laboratory Haematology, 2009, 31; 535-543.

Hotspot mutations of PIK3CA and AKT1 genes are absent in multiple myeloma. Leukemia Research, 2010, 34(6); 824-826.

N-Acetyltransferase-2 (NAT2) genotype frequency among Jordanian volunteers. Int. Jouornal of Clinical Pharmacology and Therapeutics. 2010, 48(10);688-694.

Frequent detection of Human Herpes Virus-8 (HHV-8) in bone marrow of Jordanian patients of multiple myeloma. Cancer Epidemiology. 2011, 35; 471-474.

CYP1AI, glutathione S-transferase gene polymorphisms and risk of Polycythemia vera. Cancer Epidemiology, 2012, 36 (1); 68-72.

UDP-Glucuronosyltransferase 1A4 (UGT1A4) Polymorphisms In A Jordanian Population. Molecular Biology Reports, 2012 Jul; 39(7): 7763-8.

Synthesis and biological activity assays of some new N1-(flavon-7-yl) amidrazone derivatives and related congeners. European Journal of Medicinal Chemistry, 2012, 54; 65-74.

The in vitro effect of autologous platelet lysate on different types of mesenchymal stem cells. Regenerative Research, 2012, 1(1); 25-32.

Allele and genotype frequencies of the polymorphic cytochrome P450 genes (CYP1A1, CYP3A4, CYP3A5, CYP2C9 and CYP2C19) in the Jordanian population. Mol Biol Rep. 2012, 39(10): 9423-33

Thymoquinone in liposomes: A study of loading efficiency and biological activity towards breast cancer. Drug Delivery. 2012, 19(8):371-377.

Thiopurine S-Methytransferase Gene Polymorphism in Patients with Rheumatoid Arthritis. Archives of Medical Research. 2013, (44); 105-109.

Thymoquinone efficiently inhibits the survival of EBV infected B cells and alters EBV gene expression. Integrative Cancer Therapies. 2013 12(3); 257-263.

Cancer Incidence in Jordan from 1996 to 2009 - A Comprehensive Study. Asian Pacific J Cancer Prev, 2013, 14 (6); 3527-3534.

Association of Kaposi's sarcoma-associated herpesvirus (KSHV) with bladder cancer in Croatian patients". Tumor Biology. 2014; 35(1):567-72.

Allele and Genotype Frequencies of the Polymorphic Methylenetetrahydrofolate Reductase and Colorectal Cancer among Jordanian Population. Asian Pacific Journal of Cancer Prevention, 2013, 14(8); 4559-4565.

In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker. Nucleic Acid Therapeutics, 2013, 23(6):401-7.

Preparation, characterization and antiproliferative activity of thymoquinon-β-cyclodextrin self assembly nanoparticles. Die Pharmazie, 2013, 68:939-944.

Aptamers: Promising Molecules for Cancer Stem Cell Targeting. Journal of Molecular and Genetic Medicine, 2013, 7(4):1000090.

Incidence of bcr-abl fusion transcripts in healthy individuals. Molecular Medicine Reports, 2014; (9): 1271-1276.

Functionalizing liposomes with anti-CD44 aptamer for selective targeting of cancer cells. Bioconjugate Chemistry. 2015, 26(7):1307-13.

Allele and Genotype Frequencies of the Polymorphic Methylenetetrahydrofolate Reductase and Lung Cancer in ther Jordanian Population: a Case Control Study. Asian Pac J Cancer Prev. 2015;16(8):3101-9.

The effect of various interleukins on antibody production by Epstein Barr Virus (EBV) immortalized B cells. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 2015 June; 34(3):162-8.

Ephedrine requirements during spinal anesthesia for cesarean delivery in Jordanian parturients: association with b2- adrenoceptor gene variants. Ann Saudi Med, 2016; 36(1): 29-36

Occupational exposure to pesticides and occurrence of the chromosomal translocation t(14;18) among farmers in Jordan. Toxicology Reports, 2016,(3);225–229.

Remifentanil consumption in septoplasty surgery under general anesthesia. Association with humane mu-opioid receptor gene variants. Saudi Med J 2017, 38 (2): 170-175.

Selection and Targeting of EpCAM Protien by ssDNA Aptamer. PLOS ONE. 2017, (https://doi.org/10.1371/journal.pone.0189558).

Aptamer-guided siRNA-loaded nanomedicines for systemic gene Silencing in CD-44 expressing murine triple-negative breast cancer model. Journal of Controlled Release, 2018, (271): 98–106.

Therapeutic Aptamers in Discovery, Preclinical and Clinical Stages. Advanced Drug Delivery Reviews, 2018, 134; 51–64.

Aptamers in Therapeutics and Drug Delivery (Editorial). Advanced Drug Delivery Reviews, 134 (2018); 1-2.

Developing and Characterization of Chemically Modified RNA Aptamers for Targeting Wild Type and Mutated c-KIT Receptor Tyrosine Kinases. Journal of medicinal chemistry, 2019 Aug 15. doi: 10.1021/acs.jmedchem.9b00868

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies. Molecules, 2020, 25, 3; doi:10.3390/molecules25010003.

SARS-CoV-2 entry in host cells- multiple targets for treatment and prevention. Biochimie, 175 (2020) 93-98.

Willingness to participate in genome testing: a survey of public attitudes from Qatar. Journal of Human Genetics, 2020, 1-7.

Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion. Royal Society of Chemistry, RSC Advances, 2020, 10(59): 36219-36229.

THE FUTURE OF MEDICINE, healthcare innovation through precision medicine: policy case study of Qatar. Life Sciences, Society and Policy, (2020) 16:12. https://doi.org/10.1186/s40504-020-00107-1

  • Overseas Research Studentship (ORS) award, Oxford University (1997-2000)
  • Said Foundation (KRSF) Scholarship, Oxford University (1997-2000) 
  • Winner of Abdul Hamid Shoman Award Arab Researchers Award - 2013
  • Winner of Ali Mango Award for distinguished researchers - 2012 
  • Winner of Said Foundation Award, for academic excellence - 2001
Sara Al-Khawaga

Dr. Sara Al-Khawaga

Adjunct Clinical Associate Professor

Dr. Sara Al-Khawaga

Adjunct Clinical Associate Professor

Educational Qualifications

Ph.D., Biological and Biomedical Science

Cancer Biology & Therapeutics (CBT) Program

Entity

College of Health and Life Sciences

Biography

Dr. Sara obtained her medical degree with excellence from Weill Cornell Medicine-Qatar, receiving several honors during her studies. She later completed her Ph.D. in Biological and Biomedical Sciences from Hamad bin Khalifa University in 2019. The focus of her Ph.D. was on the use of next-generation sequencing (NGS) and human pluripotent stem cell technologies in monogenic disorders. Dr. Sara has successfully published multiple high-impact publications in the field of pluripotent stem cell technology and NGS. Dr. Sara is an alumna of Harvard Medical School where she completed the Cancer Biology and Therapeutics (CBT) program during her postdoctoral fellowship with a special focus on melanoma, immunotherapy, and immune checkpoint inhibitors.

Dr. Sara further completed a postdoctoral fellowship in the Clinical Research Center in Sidra Medicine-Qatar focusing on mesenchymal stem cells isolated from adipose tissue (2015-2018). Dr. Sara joined the dermatology and venereology residency program at HMC in 2018 and served as the chief resident in 2020. Dr. Al-khawaga is currently leading the GeriDerm (Geriatric Dermatology Service) and the lead for the first National Clinical Practice Guidelines for the management of Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN) in Qatar. Dr. Sara received the National Educational Excellence in Research, an award from His Highness The Amir Shaikh Tamim Bin Hamad Al Thani in 2021, and was awarded the Regional Research award from The Arab Board in 2023, a highly competitive award from the Middle East. Dr. Sarah has recently been appointed as a professor in the College of Health and Life Sciences at Hamad Bin Khalifa University, Qatar Foundation.
 

Ph.D., Biological and Biomedical Science

College of Health and Life Sciences, Hamad Bin Khalifa University

2019

Cancer Biology & Therapeutics (CBT) Program

Harvard Medical School

2015 - 2016

Medical Doctor (MD)

Weill Cornell Medicine-Qatar

2014

  • Metabolic Syndromes Associated with Chronic Inflammatory Skin Diseases
  • Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN)

Specialist

Dermatology and Venereology, Hamad Medical Corporation

2022 - Present

Chief Resident

Dermatology and Venereology, Hamad Medical Corporation

2019 - 2020

Post-Doctoral fellow

Clinical Research Center, Translational Medicine, Sidra Medical and Research Center

  • March 2021, National Educational Excellence Award, Fourteenth Edition, Ph.D. category. Ministry of Education and Higher Education, Doha, Qatar.
  • 2023, Arab Board Best Research Award, Arab Board- Amman, Jordan.
Dr. Laith J. Abu-Raddad

Dr. Laith J. Abu-Raddad

Professor

Office location

Room B157, Weill Cornell Medicine-Qatar

Dr. Laith J. Abu-Raddad

Professor

Educational Qualifications

PhD in Physics

MS in Physics

Entity

College of Health and Life Sciences

Biography

Laith Abu-Raddad is an adjunct professor of epidemiology and biostatistics at the College of Health and Life Sciences at Hamad Bin Khalifa University. He also serves as a professor of population health sciences at Weill Cornell Medicine, Cornell University in Qatar. His expertise lies in infectious disease epidemiology, focusing on quantitative methods like mathematical modeling and biostatistics.

He has led several high-impact studies at the international and regional levels. He has published over 390 publications with a citation h-index of 97 and over 110,000 citations. His scientific research has been published in journals such as New England Journal of Medicine, Lancet, Lancet Infectious Diseases, Lancet Microbe, JAMA, Nature Medicine, JAMA Internal Medicine, Nature Communications, Clinical Infectious Diseases, Hepatology, BMC Medicine, Science Translational Medicine, and AIDS.

He has been the principal investigator of several projects funded by various funding agencies and has acted as an expert advisor and consultant for several international organizations. His research work has been key in the formulation of public health policy at the regional and international levels. The findings of his research studies have received coverage in international media such as Aljazeera, the New York Times, the BBC, and the Economist.

PhD in Physics

Florida State University, United States

2000

MS in Physics

Miami University, United States

1994

BS in Physics

University of Jordan, Jordan

1992

  • Epidemiology of COVID-19 and respiratory infections
  • Epidemiology of viral hepatitis
  • HIV
  • and other sexually transmitted infections
  • Mathematical modeling in epidemiology
  • Intervention impact assessment and health economics

Adjunct Professor of Public Health

Department of Public Health, College of Health Sciences, QU Health, Qatar University

2022 - Present

Professor of Population Health Sciences

Department of Population Health Sciences, Weill Cornell Medicine

2017 - Present

Adjunct Professor

College of Health and Life Sciences, Hamad Bin Khalifa University

2015 - Present

Associate Professor of Healthcare Policy and Research

Department of Healthcare Policy and Research, Weill Cornell Medicine, Cornell University, United States

2012 - 2017

Assistant Professor of Public Health

Department of Public Health, Weill Cornell Medicine, Cornell University, United States

2008 - 2012

  • 2019; Excellence in Educational Innovation, Weill Cornell Medicine-Qatar, Doha, Qatar.
  • 2014, 2015, 2018, 2019; Senior List Award, Weill Cornell Medicine-Qatar, Doha, Qatar.
  • 2013; Best Research Team of the Year 2013 Award, Qatar National Research Fund, Doha, Qatar.
  • 2010, 2011, 2012, 2013, 2014, 2016, and 2017; Excellence in Teaching Award, Weill Cornell Medicine-Qatar, Doha, Qatar.
  • 2000: Dirac-Hellmann Award in Theoretical Physics, Florida State University, Florida, United States