Dr. Omar Albagha | Hamad Bin Khalifa University
Hamad Bin Khalifa University

FACULTY BIOGRAPHIES

Dr. Omar Albagha

Dr. Omar Albagha


Professor
College of Health and Life Sciences

  • Phone+ 974 44542974
  • Office locationLAS Building B137

Biography

Dr. Omar Albagha received his PhD scholarship to investigate genetic susceptibility to osteoporosis at the University of Aberdeen. After completing his PhD degree in 2001, he worked as a postdoctoral researcher until 2002, when he was appointed as an Arthritis Research UK lecturer (Assistant Professor) in Genetics of Bone disease at the Institute of Medical Sciences, University of Aberdeen, UK. In 2005, he moved to the University of Edinburgh as a Principal Investigator/Group Leader at the Centre for Genomic and Experimental Medicine (CGEM). In 2014, he was appointed the Associate Director of the Paget’s Association Centre of Excellence, Edinburgh.

In early 2017, Dr. Albagha joined Hamad Bin Khalifa University (HBKU) as a Principal Investigator at the Qatar Biomedical Research Institute (QBRI), and in 2019 he joined the College of Health and Life Sciences at HBKU as a Professor of Genomic and Precision Medicine. His current research focuses on Genomic Medicine, aiming at understanding the genetic determinants of complex diseases with emphasis on Type 2 Diabetes and cardiovascular diseases. He has active collaborations with Qatar Genome Project to investigate genetics of disease-related traits in Qatar. He has published in high impact journals (Nature Genetics, JAMA, Cell Reports) and his work has been featured in news outlets such as the BBC and other international media. Dr. Albagha has received many awards from international organizations, including the European Calcified Tissue Society (ECTS) and the American Society for Bone and Mineral Research (ASBMR). He has obtained multiple research grants totaling over US$ 10 million, including the highly prestigious European Research Council (ERC) Consolidator fellowship.

 


Research Interests

  • The genetic architecture of health-related traits in the Qatari population.
  • Identification of genetic and epigenetic factors conferring susceptibility to Type 2 diabetes
  • Personalized care for Qatari patients with genetic predisposition to hypercholesterolemia
  • Identification of genetic and epigenetic factors contributing to Autism Spectrum Disorder

Experience

Professor

Hamad Bin Khalifa University

2019 - Present
  • Principle Investigator

    Qatar Biomedical Research Institute

    2017 - 2019
  • Principal Investigator in Genetics and Functional Genomics

    Institute of Genetics and Molecular Medicine, University of Edinburgh, U.K. (on Leave of Absence)

    2005 - present
  • Lecturer (Assistant Professor)

    Institute of Medical Sciences, University of Aberdeen, UK

    2002 - 2005
  • Postdoctoral Research Fellow

    Institute of Medical Sciences, University of Aberdeen, UK

    2001 - 2002

Education

PhD

University of Aberdeen, U.K.; Genetics (Medical Sciences)

2001
  • MSc

    University of Aberdeen, U.K. Medical Molecular Genetics

    1997
  • BSc

    University of Jordan, Jordan Medical Technology (Distinction)

    1996

Selected Publications

  • Smatti MK, Al-Sarraj YA, Albagha O#, Yassine HM. Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.

    Front Genet. 2020 Oct 2;11:578523. doi: 10.3389/fgene.2020.578523. #Corresponding author.

    2020
  • Al-Khelaifi F, Diboun I, Donati F, Botrè F, Abraham D, Hingorani A, Albagha O, Georgakopoulos C, Suhre K, Yousri NA, Elrayess MA.

    Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance. Sci Rep. 2019 Dec 27;9(1):19889. doi: 10.1038/s41598-019-56496-7.

    2019
  • Alonso N, Estrada K, Albagha OME, et al. Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

    Ann Rheum Dis 2018 Mar;77(3):378-385

    2018
  • Vallet M, Soares DC, Wani S, Sophocleous A, Warner J, Salter DM, Ralston SH, and Albagha OM

    Targeted sequencing of the Paget's disease-associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone. Hum Mol Genet. 2015, 24(11):3286-95

    2015
  • Haycock PC,..., Albagha O.M.E, et al. (The Telomeres Mendelian Randomisation Collaboration).

    Association between telomere length and risk of cancer and non-neoplastic diseases. JAMA Oncology. 2017; 3(5):636-651.

    2017
  • Albagha OM*, Wani SE, Visconti MR, et al

    (The Telomeres Mendelian Randomisation Collaboration). Association between telomere length and risk of cancer and non-neoplastic diseases. JAMA Oncology. 2017; 3(5):636-651.

    2017
  • Obaid R, Wani S, Azfer A, Hurd T, Jones R, Cohen P, Ralston SH, and Albagha O.M.E.

    Optineurin negatively regulates osteoclast differentiation by modulating NFκB and Interferon signalling: implications for Paget's disease. Cell Reports 2015, 13:1-7.

    2015
  • Vallet M, Soares DC, Wani S, Sophocleous A, Warner J, Salter DM, Ralston SH, and Albagha OM.

    Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone. Hum Mol Genet. 2015, 24(11):3286-95

    2015
  • Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, et al (The GEFOS consortium).

    New Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics, 2012, 44(5):491-501.

    2012
  • Albagha OM#, Wani SE, Visconti MR, et al. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.

    Nature Genetics. 2011, 43(7):685-689. Selected by F1000 Prime, #Corresponding author.

    2011
  • Albagha OM, Visconti MR, Alonso N, et al. Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone.

    Nature Genetics. 2010, 42(6):520-4. Selected by F1000 Prime.

    2010