الدكتور يونغزو بارك | جامعة حمد بن خليفة

معهد قطر لبحوث الطب الحيوي معهد قطر لبحوث الطب الحيوي

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  • القائمة
  • بحث
  • الموارد
Hamad Bin Khalifa University

أعضاء هيئة التدريس

الدكتور يونغزو بارك

الدكتور يونغزو بارك (PhD)

عالم
مركز بحوث الاضطرابات العصبية
معهد قطر لبحوث الطب الحيوي
كلية العلوم الصحية والحيوية
  • الهاتف50 156 360
  • موقع المكتبRC-B2-1428

السيرة الذاتية

Dr. Park’s research is focused on biomarkers and treatment for neurodegenerative and neurodevelopmental disorders including autism spectrum disorder (ASD). He received his PhD in investigating exocytosis and plasticity of vesicle fusion using electrophysiology and live cell imaging at the POSTECH (Pohang University of Science and Technology), South Korea, after which he worked as a postdoctoral researcher at the Max-Planck-Institute for Biophysical Chemistry, Germany, being mentored by Prof. Reinhard Jahn, a world-renowned scientist with his pioneering research into fusion and neurotransmitter release. Dr. Park was appointed Assistant Professor at the Department of Molecular Biology and Genetics at the Koç University, Istanbul, Turkey, and in 2019, he moved to Hamad Bin Khalifa University (HBKU) as a Scientist at QBRI and is co-affiliated at the College of Health & Life Sciences, HBKU as an Assistant Professor, working on the development of biomarkers and treatment for ASD, Alzheimer's disease, and Parkinson’s disease.

 

الاهتمامات البحثية

  • Modeling neurological disorders using human induced pluripotent stem cells (hiPSC)‐derived neurons and synthetic biology
  • Extracellular vesicle biomarkers for autism spectrum disorder (ASD)
  • Molecular mechanisms of neurodegenerative diseases and development of therapeutics
  • MicroRNA exocytosis by vesicle fusion (exosome-independent) in neurons and neuroendocrine cells

الخبرات

Scientist

Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU)

2019 – Present

  • Joint Assistant Professor

    College of Health & Life Sciences, Hamad Bin Khalifa University (HBKU)

    2019 – Present

  • Assistant Professor

    Department of Molecular Biology and Genetics, Koç University, Istanbul, Turkey

    2019 – 2017

  • Assistant Professor

    Izmir International Biomedicine and Genome Institute, Turkey

    2017 – 2015

  • Postdoctoral researcher

    Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

    2015 – 2009

المؤهلات العلمية

PhD in Molecular Neurobiology

POSTECH (Pohang University of Science and Technology), South Korea

2009

  • BS in Life Science

    Handong Global University, South Korea

    2001

المؤلفات المختارة

  • Shin KC, Ali G, Ali Moussa HY, Gupta V, de la Fuente A, Kim HG, Stanton LW, Park Y#. Deletion of TRPC6, an autism risk gene, induces hyperexcitability in cortical neurons derived from human pluripotent stem cells. Mol Neurobiol. 2023 Dec;60(12):7297-7308.

  • Ali Moussa HY, Shin KC, Ponraj J, Kim SJ, Ryu JK, Mansour S, Park Y#. Requirement of cholesterol for calcium-dependent vesicle fusion by strengthening synaptotagmin-1-induced membrane bending. Adv Sci. 2023 May;10(15):e2206823. Highlighted as a Frontispiece.

  • Ali Moussa HY, Park Y#. Electrostatic regulation of the cis- and trans-membrane interactions of synaptotagmin-1. Sci Rep. 2022 Dec 27;12(1):22407.

  • Park Y, Seo JB, Fraind A, Pérez-Lara A, Yavuz H, Han K, Jung SR, Kattan I, Walla PJ, Choi MY, Cafiso DS, Koh DS, Jahn R. Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength. Nature Struct Mol Biol. 2015 Oct;22(10):815-823.

  • Park Y, Hernandez J. M, van den Bogaart G, Ahmed S, Holt M, Riedel D, and Jahn R. Controlling synaptotagmin activity by electrostatic screening. Nature Struct Mol Biol. 2012 Oct;19(10):991-997.

  • Complete Publication Listing(s): NCBI
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