3:00 pm - 3:30 pm
Breast cancer remains one of the deadliest cancers worldwide. While much work has gone into understanding the molecular mechanisms underlying breast cancer development and progression, it is clear that more work needs to be done, especially on the regulation of cell death in breast cancer.
This session will present findings highlighting a crosstalk between the RNA binding proteins, such as Hu antigen R (HuR) and the nuclear envelope in the context of breast cancer cell death and senescence.
3:30 pm - 4:00 pm
Disturbances in lipid metabolism are associated with cardiometabolic disease, including obesity, diabetes, and cardiovascular disease. The inhibition of lipid metabolism has recently emerged as a potential anti-cancer strategy.
This session will highlight how a family of transcription factors that control cholesterol and fatty acid metabolism, the SREBPs, provide a link between lipid metabolism and cell proliferation.