Quantum Sensing Probes for Diagnostics and Therapies

Biological imaging techniques like optical microscopy and magnetic resonance imaging have been crucial for diagnosing diseases and developing drugs. These methods typically rely on probes (molecules or nanoparticles) that target specific elements, such as cancer cells. However, current probes cannot remotely control individual biomolecules to influence specific biochemical reactions. This remote control of biomolecules, particularly proteins, represents a frontier in biomedical research, offering potential breakthroughs in personalized medicine and disease treatment. Indeed, many biological processes, including diseases, are driven by biochemical reactions, and manipulating biomolecules could provide unprecedented control over biological systems.

Quantum sensors, like nanodiamonds, have shown promise in detecting individual molecules and spins inside cells, but remain too large to manipulate proteins directly. To address this, new quantum sensors with nanometer precision are needed.

This research project aims to propose strategies to design and produce probes that could not only act as quantum sensors, but also are capable of manipulating individual biomolecules.