Dr. Georges M. Nemer is the interim Dean at the College of Health and Life Sciences. He began his official role in January 2022 following the leave of the founding Dean, Dr. Edward Stuenkel. Professor Nemer has been leading the division of Genomics and Translational Biomedicine at the College since 2019.
Despite the COVID years, the success of the division was unprecedented in securing research funds, publishing high-impact factor journals, and graduating excellent students. Previously Dr. Nemer was the Director of Basic Science Affairs at the American University of Beirut where he mentored more than 40 graduate students, 20 postdocs in biochemistry and molecular genetics, and 16 classes of Med I students.
He has published over 120 papers in areas related to Congenital Heart Diseases and other inherited rare genetic disorders (Google Scholar: 130+ pubs, Total Citations ~ 5000, h-index 32, i10-index 68; ResearchGate: RG Score 40 (publication reads ~50,000) and book chapters. He served on the Editorial board of Scientific Reports and Frontiers in Cardiovascular Medicine and is a member of the community of experts at the European Science Foundation, the European Society of Cardiology, and the American and European Societies of Human Genetics.
Understanding the basis of congenital heart disease (CHD) requires a better understanding of key events during heart development. Given the fact that CHDs are still the leading cause of death in neonates, my primary research theme focuses on using basic genetics, and biochemical approaches to better understand these defects and ultimately try to offer better diagnosis, treatment, and foll
American University of Beirut, Lebanon
2011 - 2019Department of Biochemistry and Molecular Genetics, American University of Beirut, Lebanon
2015 - 2019Department of Biochemistry, American University of Beirut, Lebanon
2008 - 2015Department of Biochemistry, American University of Beirut, Lebanon
2002 - 2008Université de Montréal, Montreal, CANADA
1996 - 2002Université de Montréal, Montreal, CANADA
1994 - 1996American University of Beirut (AUB), Beirut, LEBANON
1989 - 1992Mont-La-Salle, Aïn Saadé, Lebanon
1989Front Cardiovasc Med. 2019 Jul 16;6:98. doi: 10.3389/fcvm.2019.00098. eCollection
2019Three novel genes tied to mandibular prognathism in East-Mediterranean families Am J Orthod Dentofacial Orthop. 2019 Jul;156(1):104-112.e3. doi: 10.1016/j.ajodo.2018.08.020.
2019Int J Mol Sci. 2019 Mar 7;20(5). pii: E1159. doi: 10.3390/ijms20051159.
2019An Emerging Role for the FOXC1/NFATC1 Genetic Axis. J Dermatol Sci. 2018 Dec;92(3):237-244. doi: 10.1016/j.jdermsci.2018.11.003
2018Transcriptomic alterations in lung adenocarcinoma unveil new mechanisms targeted by the TBX2 subfamily of tumor suppressor genes Front Oncol. 2018 Oct 30;8:482. doi: 10.3389/fonc.2018.00482.
2018BMC Med Genet. 2018 May 30;19(1):89. doi: 10.1186/s12881-018-0608-7.
2018Potential Roles for NFATC1 and DPT in the Phenotypic Variations. Front Cardiovasc Med. 2017 Sep 20;4:58. doi:10.3389/fcvm.2017.00058.
2017A high-potential marker for early detection. Oncotarget. 2017 Aug 4;8(40):68230-68241. doi: 10.18632/oncotarget.19938.
2017A Hand to TBX5 explains the link between Thalidomide and cardiac diseases. Sci Rep. 2017 May 3;7(1):1416. doi: 10.1038/s41598-017-01641-3.
2017and Kurban M. Mutations in the ABCG8 Gene are Associated with Sitosterolemia in the Homozygous Form and Xanthelasmas in the Heterozygous Form. Eur J Dermatol. 2017 Jul 25. doi: 10.1684/ejd.2017.3087.
2017Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis Hum Mol Genet. Aug 18. pii: ddw277.
Variable expressivity and co-occurrence of LDLR and LDLRAP1 mutations in familial hypercholesterolemia: failure of the dominant and recessive dichotomy. Mol Genet Genomic Med. 24;4(3):283-91. doi: 10.1002/mgg3.203
GATA5 mutation homozygosity linked to a double outlet right ventricle phenotype in a Lebanese patient. Mol Genet Genomic Med. 20;4(2):160-71. doi: 10.1002/mgg3.190
The Muscle-Bound Heart. Card Electrophysiol Clin. 8(1):223-31. doi: 10.1016/j.ccep.2015.10.034
Nkx2-5 Mutations in an Inbred Consanguineous Population: Genetic and Phenotypic Diversity. Sci Rep. Mar 6;5:8848. doi: 10.1038/srep08848, 2015
2015GATA4 Loss-of-Function Mutations Underlie Familial Tetralogy of FALLOT. Hum Mutat. Sep 2. doi: 10.1002/humu.22434. [Epub ahead of print], 2013
2013The Role of Dihydroceramide Desaturase and Transcriptional Factors NFATC and Hand2 in the Hypoxic Mouse Heart. DNA Cell Biol. 2013 Jun;32(6):310-9
2013Two heterozygous mutations in NFATC1 in a patient with tricuspid atresia. PLoS One. 7(11):e49532. doi: 10.1371/journal.pone.0049532. (2012)
2012Bitar F. Research in Congenital Heart Disease: A Comparative Bibliometric Analysis Between Developing and Developed Countries. Pediatr Cardiol. 34(2):375-82. (2012)
2012The Lebanese Allele at the LDLR in Normocholesterolemic People Merits Reconsideration of Genotype Phenotype Correlations in Familial Hypercholesterolemia. Endocrine. 42(2):445-8. (2012)
2012A Focus on the Eastern Mediterranean Region. Journal of Nutrition and Metabolism Volume 2012, Article ID 109037, 19 pages) (2012)
2012Bioorganic and Medicinal Chemistry 19(5):1734-42 (2011)
2011Homozygous familial hypercholesterolemia in Lebanon: A genotype/phenotype correlation. Mol Genet Metab. 102(2):181-8 (2011)
2011Distinct Expression and Function of Alternatevily Spliced Tbx5 Isoforms in Cell Growth and Differentiation. Mol Cell Biol. 28(12):4052-67 (2008)
2008A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot. Human Mutation 27(3):293-4 (2006)
2006Cooperative interaction between GATA-5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells. Development 129, 4045-4055 (2002)
2002A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease. Cell 106(6), pp 709-721 (2001)
2001