Dr. Ahmed Abdelaal received his bachelor’s and master’s degrees in Anatomy and Embryology from Suez Canal University, Ismailia, Egypt where his research focused on the prenatal development of the endocrine glands. He was awarded the Chinese Scholarship Council (CSC) fellowship and obtained his PhD in Developmental Biology in 2015 from Yangzhou University (China), where he gained vast experience in the generation and characterization of induced pluripotent stem cells (iPSCs). He worked on the screening of several pathways and genes that are involved in controlling the differentiation of embryonic stem cells into primordial germ stem cells (PGSCs) and subsequently to the spermatogonial stem cells (SSCs) based on RNA-Seq and DNA microarray revealing a way to solve the hurdles of male sterility and infertility.
Dr. Abdelaal joined Qatar Biomedical Research Institute (QBRI) as a postdoctoral researcher from March 2017 until January 2022 and was involved in several projects aimed to understand the pathophysiology of some incurable diseases using the patient derived iPSCs such as diabetes and autism spectrum disorder (ASD).
Currently, Dr. Abdelaal is the core manager of the QBRI stem cell core since February 2022, as well as an assistant professor at the Faculty of Veterinary medicine, Suez Canal University in Egypt.
His scientific performance records are accentuated by his peer-reviewed papers published in high-impact factor journals.
Generation of patient specific induced pluripotent stem cells (iPSCs) and its use for understanding the pathophysiology and mechanisms of several diseases including insulin resistance, diabetes and neurological disorders such as the autism spectrum disorder ASD.
Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar2017 - Present
Faculty of Veterinary medicine; Suez Canal University, Egypt2021 - Present
Faculty of Veterinary medicine; Suez Canal University, Egypt2015 - 2021
Faculty of Veterinary medicine; Suez Canal University, Egypt2009 - 2015
Faculty of Veterinary medicine; Suez Canal University, Egypt2006 - 2009
Yangzhou University; Yangzhou, Jiangsu, China2015
Suez Canal University, Ismailia, Egypt2009
Suez Canal University, Ismailia, Egypt2005
Aberrant development of pancreatic beta cells derived from patient-specific iPSCs with FOXA2 haploinsufficiency; Cell Death Dis 12, 103 (2021). https://doi.org/10.1038/s41419-021-03390-82021
Human induced pluripotent stem cell line (QBRIi013-A) derivation from a 6-year-old female diagnosed with autism spectrum disorder (ASD) and intellectual disability (ID; Stem Cell Research 56: 102500; DOI: https://doi.org/10.1016/j.scr.2021.1025002021
An induced pluripotent stem cell line derived from a patient with neonatal diabetes and Fanconi-Bickel syndrome caused by a homozygous mutation in the SLC2A2 gene; Stem Cell Research 54(10):102433; DOI: 10.1016/j.scr.2021.1024332021
"Circulating Non-Coding RNAs as a Signature of Autism Spectrum Disorder Symptomatology" International Journal of Molecular Sciences 22, no. 12: 6549. ; https://doi.org/10.3390/ijms221265492021
Keratinocytes derived from patient-specific iPSCs recapitulate the genetic signature of psoriasis disease; Stem cells and development 29(7)2020
Crucial Genes and Pathways in Chicken Germ Stem Cells Differentiation; Journal of Biological Chemistry; DOI:10.1074/jbc.M114.6014012015
Pluripotent State Induction in Mouse Embryonic Fibroblast Using mRNAs of Reprogramming Factors. International Journal of Molecular Sciences; 15(12): 21840-64; DOI: 10.3390/ijms1512218402014