Balasubramanian Moovarkumudalvan | Hamad Bin Khalifa University

College of Health and Life Sciences CHLS Hamad Bin Khalifa University Hamad Bin Khalifa University

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FACULTY BIOGRAPHIES

Balasubramanian Moovarkumudalvan

Balasubramanian Moovarkumudalvan (PhD)

Postdoc
College of Health and Life Sciences
  • Phone44 541 749
  • Office locationLAS Building, First Floor

Biography

Dr. Balasubramanian Moovarkumudalvan pursued his Bachelor’s in Physics (2002) and Master’s in Biophysics (2004) from University of Madras, India, where he also obtained his PhD in ‘Crystallography & Biophysics’ in 2010. His doctoral work involved Crystallographic Studies on Low and High Oxygen Affinity Hemoglobin. Dr. Balasubramian is a Postdoctoral Researcher at the College of Health and Life Sciences. His research is aimed to identify the regulatory interactions by using Promoter Capture Hi-C (PCHi-C) method in diseases such as leukemia. His research contributions have led to around 20 Protein Data Bank Entries and several publications including a book chapter in reputed international journals.

 

Research Interests

  • Genome Informatics
  • Structural Bioinformatics
  • Structural Biology
  • Biophysics
  • Protein X-Ray Crystallography
  • Protein-Protein / Protein-DNA Interactions

Experience

Postdoctoral Researcher

Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), Qatar.

2019 - Present

  • Senior Research Associate

    Carnegie Mellon University - Qatar (CMU-Q), Qatar.

    2018 - 2019

  • Postdoctoral Researcher

    Qatar Biomedical Research Institute (QBRI), Qatar Foundation (QF), Qatar.

    2013 - 2018

  • Postdoctoral Fellow

    Genome Institute of Singapore (GIS), Agency for Science, Technology And Research (A*STAR), Singapore.

    2010 - 2013

  • CSIR - Senior Research Fellow

    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Tamil Nadu, India.

    2008 - 2010

  • UGC - Project Fellow

    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Tamil Nadu, India.

    2007 - 2008

  • Research Scholar

    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Tamil Nadu, India.

    2005 - 2007

Education

Ph. D. (Crystallography and Biophysics)

Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Tamil Nadu, India.

2010

  • M.Sc., (Biophysics)

    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Tamil Nadu, India.

    2004

  • B.Sc., (Physics)

    University of Madras, Tamil Nadu, India.

    2002

Selected Publications

  • Abdurrahman Elbasir, *Balasubramanian Moovarkumudalvan, Khalid Kunji, Prasanna R. Kolatkar, Raghvendra Mall and Halima Bensmail.

    DeepCrystal: A Deep Learning Framework for Sequence Based Protein Crystallization Prediction. Bioinformatics, 16, 2216-2225. (*Equally Contributing First Author) URL: https://doi.org/10.1093/bioinformatics/bty953

     2019

  • Prasanna R. Kolatkar, Balasubramanian Moovarkumudalvan, Essam M. Abdelalim and Mohamed M. Emara.

    Chapter 2: Three-dimensional Structure of SOX protein-DNA Complexes. In: Prof. Hisato Kondoh & Prof. Robin Lovell-Badge (Eds), 
Sox2: Biology and Role in Development and Disease. London: Elsevier. p15-24. 
URL: https://doi.org/10.1016/B978-0-12-800352-7.00002-5

     2016

  • Saravanan Vivekanandan, Balasubramanian Moovarkumudalvan, Julien Lescar and Prasanna R. Kolatkar.

    Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA. Acta Cryst. F71, 1437-1441. URL: https://doi.org/10.1107/S2053230X1501969X

     2015

  • Balasubramanian Moovarkumudalvan, Sathya Moorthy Ponnuraj, Neelagandan Kamariah, Ramya Ramadoss, Prasanna R. Kolatkar and M. N. Ponnuswamy.

    Structure of liganded T-state hemoglobin from Cat (Felis silvestris catus), a low oxygen-affinity species, in two different crystal forms. Acta Cryst. D70, 1898-1906. (*Corresponding author). URL: https://doi.org/10.1107/S139900471400916X

     2014

  • Neelagandan Kamariah, Sathya Moorthy Ponnuraj, Balasubramanian Moovarkumudalvan and M. N. Ponnuswamy.

    Structural studies on a low oxygen affinity hemoglobin from mammalian species: Sheep (Ovis aries). Biochem. Biophys. Res. Commun. 450, 36-41. URL: https://doi.org/10.1016/j.bbrc.2014.05.062

    2014

  • P. Ramesh, S.S. Sundaresan, Pon. Sathya Moorthy, M. Balasubramanian and 
M. N. Ponnuswamy.

    Structural studies of hemoglobin from pisces species Shortfin mako shark (Isurus oxyrinchus) at 1.9Ǻ resolution. Journal of Synchrotron Radiation, 20, 843-847. URL: https://doi.org/10.1107/S0909049513021572

     2013

  • M. Balasubramanian, Pon. Sathya Moorthy, K. Neelagandan and M. N. Ponnuswamy.

    Purification, crystallization and preliminary crystallographic study of hemoglobin from camel (Camelus dromedarius): A high oxygen-affinity lowland species. Acta Cryst. F65, 773-775. URL: https://doi.org/10.1107/S1744309109024154

     2009
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